Meta AnalysisID 5907

参桂胶囊治疗慢性心力衰竭的疗效与安全性评价:随机对照试验的系统评价与Meta分析

CRD42023390409

The aim of this meta-analysis of randomized controlled trials is to evaluate the efficacy and safety of Shengui capsule for coronary heart failure

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Record Fields

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Meta Analysis Id
5907
Evidence Id
14465
Core Evidence Id
14465
Source Meta Analysis Id
5890
Herb2 Meta Analysis Id
HBMA005890
Crd Id
CRD42023390409
Title
Efficacy and safety evaluation of Shengui capsule for chronic heart failure: A systematic review and meta-analysis of randomised controlled trials
Review Question
The aim of this meta-analysis of randomized controlled trials is to evaluate the efficacy and safety of Shengui capsule for coronary heart failure
Study Type Included
Randomized controlled trials (RCTs) will be included.
Condition Being Studied
Heart failure is the most common cardiovascular reason for hospital admission for people older than 60 years of age, which characterized by dyspnea, fatigue, and signs of volume overload. Many conditions, such as coronary artery disease, hypertension, valvular heart disease, and diabetes mellitus, can cause or lead to decompensation of chronic heart failure. Especially, coronary artery disease is the most common cause of heart failure. Studies have shown that complementary and alternative therapy plays an advantage in improving symptoms and reducing side effects in patients with coronary heart failure (CHF). Shengui capsule is widely used in the treatment of CHF in China.
Participant
Adults with coronary heart failure (as diagnosed by a clinician, or using any recognized diagnostic criteria) will be included.
Animal
Human Disease Modelled
Intervention
Shengui capsule is the main intervention.
Comparator Control
Usual care and medications such as diuretics, angiotensin converting enzyme inhibitors (ACEIs), or angiotensin II receptor blockers (ARBs), β-receptor blocker, aldosterone-receptor blocker, digoxin, etc.
Main Outcome
LVEF, adverse events
Outcome Measure
Additional Outcome
LVESD, LVEDD, brain natriuretic peptide (BNP), hs-CRP, effective rate of heart function improvement
Study Method
Keyword
Chronic Disease; Heart; Heart Failure; Humans; Randomized Controlled Trials as Topic; Thorax
Contact
Jiaqi Yan [email protected]
Organisational Affiliation
Guangzhou University of Chinese Medicine
Funding Source
This work is funded by the grants from the National Natural Science Foundation of China (No.82174156), Guangzhou Science and Technology Project (No. 202002030432), and Key-Area Research and Development Program of Guangdong Province (No.2020B1111100004).
Other Selection Criteria
Final Publication
Same Topic Review
Published Protocol
Review Type
Language
English
Country
China
Review Stage
Review Ongoing
First Submission Date
2023-01-09
Registration Date
2023-01-20
Anticipated Start Date
2023-01-09
Anticipated Completion Date
2024-01-03
Title Cn
参桂胶囊治疗慢性心力衰竭的疗效与安全性评价:随机对照试验的系统评价与Meta分析
Title En
Efficacy and safety evaluation of Shengui capsule for chronic heart failure: A systematic review and meta-analysis of randomised controlled trials
Bilingual Status
complete