Meta AnalysisID 5888
中药注射剂治疗脓毒症诱导的心肌功能障碍的疗效和安全性的系统评价与网状Meta分析
CRD42022329765
1.Can Chinese medicine injections improve sepsis survival and reduce mortality? 2.Does it reduce the risk of sepsis-induced myocardial injury compared to conventional treatment? 3.Is it safe to use Traditional Chinese me
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Record Fields
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- Meta Analysis Id
- 5888
- Evidence Id
- 14446
- Core Evidence Id
- 14446
- Source Meta Analysis Id
- 5864
- Herb2 Meta Analysis Id
- HBMA005864
- Crd Id
- CRD42022329765
- Title
- A systematic review and network meta-analysis for the efficacy and safety of traditional Chinese medicine injections for sepsis-induced myocardial dysfunction
- Review Question
- 1.Can Chinese medicine injections improve sepsis survival and reduce mortality? 2.Does it reduce the risk of sepsis-induced myocardial injury compared to conventional treatment? 3.Is it safe to use Traditional Chinese medicine injections for sepsis-induced myocardial injury? 4.Compare the safety and efficacy of different Traditional Chinese medicine injections.
- Study Type Included
- Randomized controlled trials (RCTs) will be included. Observational, cohort, case-control, case series, qualitative and laboratory studies, and uncontrolled trials will be excluded.
- Condition Being Studied
- Sepsis-induced myocardial dysfunction is a common complication of sepsis, and its mortality rate is increasing significantly.
- Participant
- Patients who meet the diagnostic criteria for sepsis and have myocardial dysfunction will be included.
- Animal
- Human Disease Modelled
- Intervention
- Initially retrieved Traditional Chinese Medicine Injections for the treatment of sepsis-induced myocardial dysfunction, including Xuebijing injection, Xinmailong injection, Shenfu injection, Shenmai injection, Shuxuening injection, Chuanxiongqin injection, Huangqi injection.
- Comparator Control
- Conventional treatment.
- Main Outcome
- 1.Case fatality rate and total effective rate evaluation. 2.Adverse Events.
- Outcome Measure
- Additional Outcome
- 1. APACHE-II score (Acute Physiology and Chronic Health Evaluation) 2. SOFA score (Sequential Organ Failure Assessment)
- Study Method
- Intervention, Meta-analysis, Network meta-analysis, Systematic review
- Keyword
- Drugs, Chinese Herbal; Humans; Medicine, Chinese Traditional; Network Meta-Analysis; Sepsis
- Contact
- jingwen Xue [email protected]
- Organisational Affiliation
- Beijing University of Chinese Medicine https://www.bucm.edu.cn/
- Funding Source
- This study is supported by a project of National Key R&D Program of China（2018YFC1705902）
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- Chinese-Simplified, English
- Country
- China
- Review Stage
- Review Ongoing
- First Submission Date
- 2022-05-02
- Registration Date
- 2022-05-13
- Anticipated Start Date
- 2022-06-01
- Anticipated Completion Date
- 2022-12-01
- Title Cn
- 中药注射剂治疗脓毒症诱导的心肌功能障碍的疗效和安全性的系统评价与网状Meta分析
- Title En
- A systematic review and network meta-analysis for the efficacy and safety of traditional Chinese medicine injections for sepsis-induced myocardial dysfunction
- Bilingual Status
- complete