Meta AnalysisID 5656
安宫牛黄丸辅助治疗创伤性颅脑损伤：随机对照试验的Meta分析
CRD42020177087
The purpose of this review is to evaluate the efficacy and safety of angong niuhuang pill as an adjuvant therapy in patients with traumatic craniocerebral injury.
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Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 5656
- Evidence Id
- 14214
- Core Evidence Id
- 14214
- Source Meta Analysis Id
- 5637
- Herb2 Meta Analysis Id
- HBMA005637
- Crd Id
- CRD42020177087
- Title
- Adjuvant treatment with angong niuhuang Pill for traumatic craniocerebral injury:A meta-analysis of randomized controlled trials
- Review Question
- The purpose of this review is to evaluate the efficacy and safety of angong niuhuang pill as an adjuvant therapy in patients with traumatic craniocerebral injury.
- Study Type Included
- This study will only consider randomized controlled trials (RCTs). Any other studies will be not considered, such as non-clinical studies, non-controlled trials, crossover studies, non-RCTs, and quasi-RCTs.
- Condition Being Studied
- Traumatic craniocerebral injury is one of the leading causes of death and disability in both developing and developed countries.Angong Niuhuang Pill (ANP), a well-known traditional Chinese patent medicine, has been widely used in China. It contains Buffalo Horn, Calculus Bovis, Radix Curcumae, Radix Scutellariae, Rhizoma Coptidis, Realgar,Fructus Gardeniae, Cinnabaris, Borneolum Syntheticum, Musk, and Margarita. ANP has been used to manage patients with various acute cerebrovascular diseases, such as traumatic craniocerebral injury, encephalitis, meningitis, cerebral infarction, intracerebral hemorrhage.
- Participant
- Adult participants (≥18 years), with a confirmed diagnosis of Traumatic craniocerebral injury.
- Animal
- Human Disease Modelled
- Intervention
- Angong Niuhuang Pill + Usual treatment
- Comparator Control
- Usual treatment
- Main Outcome
- Glasgow Outcome Scale; Glasgow Coma Scale; Pulmonary infection; Mg 2+ concentration. Measures of effect A good prognosis should be based on the GOS prognosis score greater than or equal to 4. Other outcomes have been related to imaging and testing as the standard.
- Outcome Measure
- Additional Outcome
- Gastrointestinal bleeding; Liver function; Renal function; neuron-specific enolase. Measures of effect outcomes according to the clinical symptoms, related imaging and examination as the standard.
- Study Method
- Systematic review
- Keyword
- Angong Niuhuang Pill; Craniocerebral Trauma; Drugs, Chinese Herbal; Humans; Randomized Controlled Trials as Topic
- Contact
- Zhang Yongming [email protected]
- Organisational Affiliation
- Department of Neurosurgery, the second people's Hospital of Anhui Province, China.
- Funding Source
- This study was supported by the Key Research and Development Plan projects in Anhui Province Grant number(s) <span style=font-size: 14px>State the funder, grant or award number and the date of award</span> number 201904a07020108
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- China
- Review Stage
- Review Ongoing
- First Submission Date
- 2020-03-29
- Registration Date
- 2020-07-05
- Anticipated Start Date
- 2020-02-12
- Anticipated Completion Date
- 2020-05-10
- Title Cn
- 安宫牛黄丸辅助治疗创伤性颅脑损伤：随机对照试验的Meta分析
- Title En
- Adjuvant treatment with angong niuhuang Pill for traumatic craniocerebral injury:A meta-analysis of randomized controlled trials
- Bilingual Status
- complete