Meta AnalysisID 5615

玻璃体腔注射抗VEGF药物联合曲安奈德治疗糖尿病性黄斑水肿的疗效与安全性:系统评价与Meta分析

CRD42022369945

The aim of this meta-analysis of randomized controlled trials is to compare the effect and safety of intraocular injection of anti-VEGF drugs combined with triamcinolone acetonide in the treatment of Diabetic Macular Ede

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Record Fields

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Meta Analysis Id
5615
Evidence Id
14173
Core Evidence Id
14173
Source Meta Analysis Id
5597
Herb2 Meta Analysis Id
HBMA005597
Crd Id
CRD42022369945
Title
The effect and safety of intraocular injection of anti-VEGF drugs combined with triamcinolone acetonide in the treatment of Diabetic Macular Edema:A Systematic Review and Meta-analysis.
Review Question
The aim of this meta-analysis of randomized controlled trials is to compare the effect and safety of intraocular injection of anti-VEGF drugs combined with triamcinolone acetonide in the treatment of Diabetic Macular Edema.
Study Type Included
Randomized controlled trials (RCTs) will be included. The followings will be excluded: conference abstracts, RCTs, pseudo-RCTs, cohort and case-control studies, case reports, letters, systematic review, reviews, and duplicate publications
Condition Being Studied
Diabetic macular edema
Participant
Those patients with an established diagnosis of DME are included.Macular edema caused by other conditions other than diabetes are excluded.If the medicine was used in both the experimental and control groups, the study could be included. In addition to the use of DME treatment medicine, DME patients often combine with other treatment, such as hypoglycemic and antihypertensive agents and so on. If the medicine was used in both the experimental and control groups, the study could be included. If the use of this medicine is not balanced between the experimental and control groups, the study would be excluded.If the use of this medicine is not balanced between the experimental and control groups, the study would be excluded
Animal
Human Disease Modelled
Intervention
intraocular injection of anti-VEGF drugs combined with triamcinolone acetonid
Comparator Control
intraocular injection of anti-VEGF drugs alones
Main Outcome
he number of people who respond to treatment,best-corrected visual acuity (BCVA),central macular thickness(CMT).
Outcome Measure
Additional Outcome
Adverse events
Study Method
Systematic review
Keyword
Diabetes Mellitus; Diabetic Retinopathy; Humans; Injections, Intraocular; Macular Edema; Randomized Controlled Trials as Topic; Triamcinolone Acetonide
Contact
Xu Dahua [email protected]
Organisational Affiliation
Aier School of Ophthalmology, Central South University, Changsha 410000,Hunan, China.
Funding Source
Other Selection Criteria
Final Publication
Same Topic Review
Published Protocol
Review Type
Language
English
Country
China
Review Stage
Review Ongoing
First Submission Date
2022-10-24
Registration Date
2022-11-04
Anticipated Start Date
2022-10-25
Anticipated Completion Date
2023-01-20
Title Cn
玻璃体腔注射抗VEGF药物联合曲安奈德治疗糖尿病性黄斑水肿的疗效与安全性:系统评价与Meta分析
Title En
The effect and safety of intraocular injection of anti-VEGF drugs combined with triamcinolone acetonide in the treatment of Diabetic Macular Edema:A Systematic Review and Meta-analysis.
Bilingual Status
complete