Meta AnalysisID 5602

甲萘四烯酮治疗骨质疏松症的有效性和安全性:随机对照试验的系统评价与Meta分析

CRD42018097210

Is menatetrenone a both effective and safe choice for the management of osteoporosis?

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Record Fields

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Meta Analysis Id
5602
Evidence Id
14160
Core Evidence Id
14160
Source Meta Analysis Id
5586
Herb2 Meta Analysis Id
HBMA005586
Crd Id
CRD42018097210
Title
The efficacy and safety of menatetrenone in the management of osteoporosis: a systematic review and meta-analysis of randomized controlled trials
Review Question
Is menatetrenone a both effective and safe choice for the management of osteoporosis?
Study Type Included
Randomized controlled trials.
Condition Being Studied
Pharmacotherapy of osteoporosis.
Participant
Adults with osteoporosis.
Animal
Human Disease Modelled
Intervention
Menatetrenone, 45mg/day, for treating osteoporosis.
Comparator Control
Placebo or anti-osteoporotic drugs for treating osteoporosis.
Main Outcome
Fracture, vertebral fracture, non-vertebral fracture and hip fracture.
Outcome Measure
Additional Outcome
Bone mineral density (BMD), undercarboxylated osteocalcin (ucOC), ucOC/OC ratio,adverse events, adverse drug reactions, serious adverse events, gastrointestinal related adverse events and prothrombin time (PT).
Study Method
Intervention, Meta-analysis, Systematic review
Keyword
Humans; Osteoporosis; Randomized Controlled Trials as Topic; Vitamin K 2; menatetrenone
Contact
Miss Shan Su [email protected]
Organisational Affiliation
Department of Pharmacy, Peking University Third Hospital.
Funding Source
Other Selection Criteria
Final Publication
Same Topic Review
Published Protocol
Review Type
Language
English
Country
China
Review Stage
Review Ongoing
First Submission Date
2018-05-21
Registration Date
2018-06-11
Anticipated Start Date
2017-10-10
Anticipated Completion Date
2018-06-30
Title Cn
甲萘四烯酮治疗骨质疏松症的有效性和安全性:随机对照试验的系统评价与Meta分析
Title En
The efficacy and safety of menatetrenone in the management of osteoporosis: a systematic review and meta-analysis of randomized controlled trials
Bilingual Status
complete