Meta AnalysisID 5541

维生素K对伤口愈合的影响:系统评价与Meta分析

CRD42022363188

To evaluate the effect of vitamin K on wound healing by wound healing rate. We considered the wound model from rats in vivo. Context and rationale This study aimed to determine, through a meta-analysis and systematic rev

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Record Fields

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Meta Analysis Id
5541
Evidence Id
14099
Core Evidence Id
14099
Source Meta Analysis Id
5525
Herb2 Meta Analysis Id
HBMA005525
Crd Id
CRD42022363188
Title
Effect of Vitamin K on Wound Healing : A Systematic Review and Meta-Analysis
Review Question
To evaluate the effect of vitamin K on wound healing by wound healing rate. We considered the wound model from rats in vivo. Context and rationale This study aimed to determine, through a meta-analysis and systematic review, the accelerated wound contraction potentials of vitamin K on wound repairment. The outcome of this research is particularly important in the consideration of vitamin K would be used in clinic for wound repairment.
Study Type Included
Inclusion criteria: controlled studies with a separate control group Exclusion criteria: cross-over studies, studies without a separate control group.
Condition Being Studied
Participant
Animal
Inclusion criteria: wound on experimental animals(all species, all sexes) in vivo , studies contain control group Exclusion criteria: no control group
Human Disease Modelled
wound (injury)
Intervention
Inclusion criteria: durgs from vitamin K or the main component from vitamin K, drug should be used in external application Exclusion criteria: not match inclusion criteria or the drug used for oral administration
Comparator Control
Inclusion criteria: usual drugs or PBS Exclusion criteria: drugs contain vitamin K
Main Outcome
Outcome Measure
Inclusion criteria: the wound contraction (%) are extracted at the 7th day after injury, or the nearest days were used to instead when the 7th day data were unpublished Exclusion criteria: other indexes
Additional Outcome
Study Method
Keyword
Animals; Disease Models, Animal; Humans; Rats; Vitamin K; Wound Healing
Contact
SAIQING TANG [email protected]
Organisational Affiliation
Shaanxi University of Chinese Medicine
Funding Source
National Natural Science Foundation of China (82104975) Shaanxi Province Key Research and Development Program (2021SF-361) Key Research and Development Program of Xianyang (2020K02-97) Scientific Research Program Funded by Shaanxi Provincial Education Department (21JS019) Scientific Research Program funded by Health Commission of Shaanxi Province (2021A007)
Other Selection Criteria
The inclusion of articles should be original research paper ( Not review, editorial)
Final Publication
Same Topic Review
Published Protocol
Review Type
Animal model review, Experimental animal exposure review
Language
English
Country
China
Review Stage
Review Ongoing
First Submission Date
2022-09-27
Registration Date
2022-11-08
Anticipated Start Date
2022-02-01
Anticipated Completion Date
2022-12-31
Title Cn
维生素K对伤口愈合的影响:系统评价与Meta分析
Title En
Effect of Vitamin K on Wound Healing : A Systematic Review and Meta-Analysis
Bilingual Status
complete