Meta AnalysisID 5520
叶酸联合维生素B12和维生素B6补充预防卒中的疗效：一项Meta分析
CRD42022355077
This meta-analysis of randomized controlled trials was designed to assess the efficacy of folic acid in combination with vitamin B12 and vitamin B6 supplementation in stroke and to identify the target population that wou
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Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 5520
- Evidence Id
- 14078
- Core Evidence Id
- 14078
- Source Meta Analysis Id
- 5505
- Herb2 Meta Analysis Id
- HBMA005505
- Crd Id
- CRD42022355077
- Title
- Efficacy of folic acid supplementation in combination with vitamin B12 and vitamin B6 for stroke prevention: a meta-analysis
- Review Question
- This meta-analysis of randomized controlled trials was designed to assess the efficacy of folic acid in combination with vitamin B12 and vitamin B6 supplementation in stroke and to identify the target population that would benefit from this treatment.
- Study Type Included
- We will include randomized controlled trials to assess the beneficial effects of the folic acid combined with vitamin B12 and vitamin B6 supplementation.
- Condition Being Studied
- Stroke is one of the major public health problems and a leading cause of death and disability among adults worldwide. Recent studies show that the number of people affected by stroke reached 101 million and disability-adjusted life years (DALYs) reached 143 million worldwide in 2019, creating a significant disease and economic burden.
- Participant
- Inclusion: Adults.
- Animal
- Human Disease Modelled
- Intervention
- Folic acid combined with vitamin B12 and vitamin B6 supplementation.
- Comparator Control
- Placebo or very low dose control group.
- Main Outcome
- Main outcomes: all types of stroke. Measures of effect Relative risk with 95% confidence interval was used as a measure of the association between supplementation and risk of stroke.
- Outcome Measure
- Additional Outcome
- None.
- Study Method
- Meta-analysis, Systematic review
- Keyword
- Dietary Supplements; Folic Acid; Humans; Stroke; Vitamin B 12; Vitamin B 6
- Contact
- Ziyi Zhou [email protected]
- Organisational Affiliation
- Tsinghua University
- Funding Source
- No funding.
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- China
- Review Stage
- Review Ongoing
- First Submission Date
- 2022-08-22
- Registration Date
- 2022-09-01
- Anticipated Start Date
- 2022-08-15
- Anticipated Completion Date
- 2022-11-30
- Title Cn
- 叶酸联合维生素B12和维生素B6补充预防卒中的疗效：一项Meta分析
- Title En
- Efficacy of folic acid supplementation in combination with vitamin B12 and vitamin B6 for stroke prevention: a meta-analysis
- Bilingual Status
- complete