Meta AnalysisID 514
阿拉伯茶（Catha edulis）是否会增加口腔癌风险？一项系统评价与Meta分析
CRD42017082498
Does khat (Catha Edulis) chewing increase the risk of oral cancer? A systematic review and meta-analysis
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Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 514
- Evidence Id
- 9072
- Core Evidence Id
- 9072
- Source Meta Analysis Id
- 487
- Herb2 Meta Analysis Id
- HBMA000487
- Crd Id
- CRD42017082498
- Title
- Does khat (Catha Edulis) increase the risk of oral cancer? A systematic review and meta-analysis
- Review Question
- Does khat (Catha Edulis) chewing increase the risk of oral cancer? A systematic review and meta-analysis
- Study Type Included
- randomized controlled trials, controlled clinical trials, retrospective studies, cross-sectional studies, case-control all experimental studies (in vitro or animal studies) that examined cytotoxicity and genotoxicity effects of khat.
- Condition Being Studied
- Oral cancer
- Participant
- Population for human studies: Individuals who provided a history of chewing khat and those persons who had never chewed khat. participant for animal and in vitro studies : the extract of the khat leaves in the form of cell culture, organotypic tissue, animals;
- Animal
- Human Disease Modelled
- Intervention
- Intervention for human studies : Individuals who provided a history of chewing khat more frequently for at least 3 Years exposure for animal and in vitro studies : all bioanimal assay studies and in vitro studies assessed association between khat extract and cytotoxcity , genotoxicity an muatgenicity
- Comparator Control
- Comparator for human studies: a person who had never chewed khat or non-chewing sides control group for animal and in vitro studies : untreated group or vehicle group
- Main Outcome
- Outcome: histopathological changes Outcome : cytotoxicity; apoptosis
- Outcome Measure
- Additional Outcome
- Outcome: clinical mucosal changes such as white lesions
- Study Method
- Meta-analysis, Pre-clinical, Systematic review
- Keyword
- Catha; Humans; Mouth Neoplasms; Risk
- Contact
- Essam Ahmed Al-Moraissi [email protected]
- Organisational Affiliation
- faculty of dentistry -thamar uinveristy
- Funding Source
- Other Selection Criteria
- Final Publication
- Same Topic Review
- non
- Published Protocol
- Review Type
- Language
- Country
- Yemen
- Review Stage
- Review Ongoing
- First Submission Date
- 2017-11-28
- Registration Date
- 2017-12-20
- Anticipated Start Date
- 2017-11-28
- Anticipated Completion Date
- 2018-01-01
- Title Cn
- 阿拉伯茶（Catha edulis）是否会增加口腔癌风险？一项系统评价与Meta分析
- Title En
- Does khat (Catha Edulis) increase the risk of oral cancer? A systematic review and meta-analysis
- Bilingual Status
- complete