Meta AnalysisID 4895
维生素B6与肺癌风险：一项系统评价与Meta分析
CRD42018086540
Is there an association of vitamin B6 intake or blood levels of pyridoxal 5'-phosphate (the active form of vitamin B6) with the risk of lung cancer?
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Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 4895
- Evidence Id
- 13453
- Core Evidence Id
- 13453
- Source Meta Analysis Id
- 4877
- Herb2 Meta Analysis Id
- HBMA004877
- Crd Id
- CRD42018086540
- Title
- Vitamin B6 and lung cancer risk: a systematic review and meta-analysis
- Review Question
- Is there an association of vitamin B6 intake or blood levels of pyridoxal 5'-phosphate (the active form of vitamin B6) with the risk of lung cancer?
- Study Type Included
- We will include randomised trials and the observational studies (including cohort and nested case-control as well as the case-control studies) for the assessment of the association between vitamin B6 intake or the blood levels of PLP and the risk of lung cancer.
- Condition Being Studied
- Lung cancer. Vitamin B6 intake.
- Participant
- Inclusion: Adults with lung cancer and exposed to vitamin B6. Exclusion: adolesents (under 18 years of age).
- Animal
- Human Disease Modelled
- Intervention
- Intake of vitamin B6 or blood (plasma or serum) levels of PLP.
- Comparator Control
- Controls are those with the less intake of vitamin B6 or lower level of PLP for the observational studies; For the interventional studies, cases who exposed to the placebo will be considered as controls.
- Main Outcome
- Lung cancer. Measures of effect The relative risk (RR) estimates with 95% confidence intervals (CIs) will be considered as the effect measures.
- Outcome Measure
- Additional Outcome
- None.
- Study Method
- Epidemiologic, Intervention, Meta-analysis, Systematic review
- Keyword
- Humans; Lung Neoplasms; Pyridoxal Phosphate; Pyridoxine; Risk; Vitamin B 6; Vitamin B 6 Deficiency
- Contact
- Min Jiang [email protected]
- Organisational Affiliation
- Department of Epidemiology, School of Public Health, China Medical University, Shenyang, China
- Funding Source
- The National Key Research and Development Program of China（2016YFC1302501). Funding provided by Baosen Zhou.
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- Country
- China
- Review Stage
- Review Ongoing
- First Submission Date
- 2018-01-22
- Registration Date
- 2018-02-02
- Anticipated Start Date
- 2018-01-21
- Anticipated Completion Date
- 2018-06-21
- Title Cn
- 维生素B6与肺癌风险：一项系统评价与Meta分析
- Title En
- Vitamin B6 and lung cancer risk: a systematic review and meta-analysis
- Bilingual Status
- complete