Meta AnalysisID 4705

碳-13尿素呼气试验和碳-14尿素呼气试验诊断幽门螺杆菌感染准确性的系统评价和Meta分析

CRD42022354308

What is the Accuracy of 13C UBT and 14C UBT Urea Breath Tests in the Diagnosis of Helicobacter Pylori Infection

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Record Fields

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Meta Analysis Id
4705
Evidence Id
13263
Core Evidence Id
13263
Source Meta Analysis Id
4673
Herb2 Meta Analysis Id
HBMA004673
Crd Id
CRD42022354308
Title
Systematic Review and Meta-Analysis on the Accuracy of 13C UBT and 14C UBT Urea Breath Tests in the Diagnosis of Helicobacter Pylori Infection
Review Question
What is the Accuracy of 13C UBT and 14C UBT Urea Breath Tests in the Diagnosis of Helicobacter Pylori Infection
Study Type Included
The author will include cross-sectional studies with consecutive patients that evaluated the diagnostic accuracy of UBT in adult patients with dyspeptic symptoms. The author will include articles that compare 13C-UBT or 14C-UBT H. pylori test with a reference standard which is H. pylori (culture and/or histological examination) and/ or not (serologic test either blood or stool).
Condition Being Studied
Urea breath test (UBT) is a commonly used non-invasive test to diagnose Helicobacter pylori (H. pylori) infection in patients with dyspepsia. Multiple trials are available in the literature, but they reported different diagnostic accuracy estimates. The author will conduct a systemic review and meta-analysis to explore the available evidence and provide pooled diagnostic accuracy measures.
Participant
Patients underwent a urea breath test (UBT) for diagnosis of H. pylori infection.
Animal
Human Disease Modelled
Intervention
Urea breath test.
Comparator Control
13C UBT vs 14C UBT.
Main Outcome
To explore the available evidence and provide pooled diagnostic accuracy measures.
Outcome Measure
Additional Outcome
The level of UBT diagnostic accuracy for detecting H. pylori infection in patients with dyspepsia.
Study Method
Diagnostic, Meta-analysis, Systematic review
Keyword
Breath Tests; Carbon-13; Carbon-14; Helicobacter Infections; Helicobacter pylori; Humans; Urea
Contact
Layal Jambi [email protected]
Organisational Affiliation
King Saud University
Funding Source
Other Selection Criteria
Final Publication
Same Topic Review
Published Protocol
Review Type
Language
English
Country
Saudi Arabia
Review Stage
Review Ongoing
First Submission Date
2022-08-17
Registration Date
2022-08-28
Anticipated Start Date
2022-08-18
Anticipated Completion Date
2022-09-17
Title Cn
碳-13尿素呼气试验和碳-14尿素呼气试验诊断幽门螺杆菌感染准确性的系统评价和Meta分析
Title En
Systematic Review and Meta-Analysis on the Accuracy of 13C UBT and 14C UBT Urea Breath Tests in the Diagnosis of Helicobacter Pylori Infection
Bilingual Status
complete