Meta AnalysisID 4700

尿素基乳膏与塞来昔布对化疗诱导手足综合征的预防效果:一项系统评价和Meta分析

CRD42021275651

How effective is urea cream and celecoxib in preventing hand foot syndrome in cancer patients on chemotherapy?

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Record Fields

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Meta Analysis Id
4700
Evidence Id
13258
Core Evidence Id
13258
Source Meta Analysis Id
4668
Herb2 Meta Analysis Id
HBMA004668
Crd Id
CRD42021275651
Title
Prophylactic Effect of Urea-Based Cream and Celecoxib on Chemotherapy-Induced Hand-Foot Syndrome: A Systematic Review and Metaanalysis
Review Question
How effective is urea cream and celecoxib in preventing hand foot syndrome in cancer patients on chemotherapy?
Study Type Included
Randomized controlled trials only INCLUSION: (1) urea cream or celecoxib as intervention vs placebo (2) population should include cancer patients only (3) incidence of HFS as outcome
Condition Being Studied
Chemotherapy induced hand-foot syndrome
Participant
Cancer patients on Sorafenib or Capecitabine
Animal
Human Disease Modelled
Intervention
Urea cream applied on hands and feet Oral celecoxib as prophylaxis
Comparator Control
Placebo
Main Outcome
Incidence of HFS of any grade Time to development of HFS Quality of life
Outcome Measure
Additional Outcome
Study Method
Meta-analysis, Systematic review
Keyword
Antineoplastic Agents; Capecitabine; Celecoxib; Hand-Foot Syndrome; Humans; Urea
Contact
Jessa Gilda Pandy [email protected]
Organisational Affiliation
St Lukes Medical Center
Funding Source
Other Selection Criteria
Final Publication
Same Topic Review
Published Protocol
Review Type
Language
English
Country
Philippines
Review Stage
Review Ongoing
First Submission Date
2021-08-27
Registration Date
2021-09-29
Anticipated Start Date
2021-09-01
Anticipated Completion Date
2021-10-01
Title Cn
尿素基乳膏与塞来昔布对化疗诱导手足综合征的预防效果:一项系统评价和Meta分析
Title En
Prophylactic Effect of Urea-Based Cream and Celecoxib on Chemotherapy-Induced Hand-Foot Syndrome: A Systematic Review and Metaanalysis
Bilingual Status
complete