Meta AnalysisID 4607
高灵敏度基础血清甲状腺球蛋白用于检测和预测分化型甲状腺癌疾病结构证据的诊断性能：一项系统评价和Meta分析
CRD42019125092
1. In patients with differentiated thyroid cancer treated with thyroidectomy with or without radioiodine, what is the diagnostic performance of high sensitive basal serum thyroglobulin for detecting structural evidence o
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Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 4607
- Evidence Id
- 13165
- Core Evidence Id
- 13165
- Source Meta Analysis Id
- 4573
- Herb2 Meta Analysis Id
- HBMA004573
- Crd Id
- CRD42019125092
- Title
- Diagnostic performance of high sensitive basal serum thyroglobulin for detecting and predicting structural evidence of disease in differentiated thyroid cancer: a systematic review and meta-analysis
- Review Question
- 1. In patients with differentiated thyroid cancer treated with thyroidectomy with or without radioiodine, what is the diagnostic performance of high sensitive basal serum thyroglobulin for detecting structural evidence of disease at the time of thyroglobulin testing? 2. In patients with differentiated thyroid cancer treated with thyroidectomy with or without radioiodine, what is the diagnostic performance of high sensitive basal serum thyroglobulin for predicting structural evidence of disease during follow-up?
- Study Type Included
- We will include observational studies and randomized controlled trials.
- Condition Being Studied
- Differentiated thyroid cancer.
- Participant
- Inclusion: adults, children and adolescents.
- Animal
- Human Disease Modelled
- Intervention
- High sensitive basal serum thyroglobulin.
- Comparator Control
- Structural versus no evidence of disease.
- Main Outcome
- Sensitivity, specificity, positive and negative predictive value. Measures of effect Not applicable.
- Outcome Measure
- Additional Outcome
- None. Measures of effect Not applicable.
- Study Method
- Diagnostic, Meta-analysis, Systematic review
- Keyword
- Adenocarcinoma; Humans; Hypersensitivity; Thyroglobulin; Thyroid Neoplasms
- Contact
- Pierpaolo Trimboli [email protected]
- Organisational Affiliation
- None.
- Funding Source
- None.
- Other Selection Criteria
- Final Publication
- Giovanella L, Castellana M, Trimboli P. Unstimulated high-sensitive thyroglobulin is a powerful prognostic predictor in patients with thyroid cancer. Clin Chem Lab Med. 2019 Aug 24. pii: /j/cclm.ahead-of-print/cclm-2019-0654/cclm-2019-0654.xml. doi: 10.1515/cclm-2019-0654. [Epub ahead of print] https://www.degruyter.com/view/j/cclm.ahead-of-print/cclm-2019-0654/cclm-2019-0654.xml?format=INT
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- Italy, Switzerland
- Review Stage
- Review Completed published
- First Submission Date
- 2019-02-11
- Registration Date
- 2019-03-14
- Anticipated Start Date
- 2019-02-01
- Anticipated Completion Date
- 2019-04-30
- Title Cn
- 高灵敏度基础血清甲状腺球蛋白用于检测和预测分化型甲状腺癌疾病结构证据的诊断性能：一项系统评价和Meta分析
- Title En
- Diagnostic performance of high sensitive basal serum thyroglobulin for detecting and predicting structural evidence of disease in differentiated thyroid cancer: a systematic review and meta-analysis
- Bilingual Status
- complete