Meta AnalysisID 4587

术前抗甲状腺球蛋白抗体和抗TPO抗体对甲状腺乳头状癌的预后效用:一项系统评价与Meta分析

CRD42020213298

Do preoperative anti-thyroglobulin and/or anti-TPO antibodies predict clinical prognosis in patients diagnosed with papillary thyroid carcinoma?

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Record Fields

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Meta Analysis Id
4587
Evidence Id
13145
Core Evidence Id
13145
Source Meta Analysis Id
4574
Herb2 Meta Analysis Id
HBMA004574
Crd Id
CRD42020213298
Title
Prognostic utility of preoperative anti-thyroglobulin and anti-TPO antibodies in papillary thyroid carcinoma: a systematic review and meta-analysis
Review Question
Do preoperative anti-thyroglobulin and/or anti-TPO antibodies predict clinical prognosis in patients diagnosed with papillary thyroid carcinoma?
Study Type Included
Inclusion: RCTs, observational (prospective or retrospective)
Condition Being Studied
Papillary thyroid cancer
Participant
Adults (>= 18 years old) diagnosed with papillary thyroid cancer Exclusion: no adolescent populations
Animal
Human Disease Modelled
Intervention
Index prognostic factor: Preoperative anti-thyroglobulin and anti-TPO antibodies
Comparator Control
Main Outcome
Overall survival, disease-free survival, recurrence-free survival Measures of effect We will calculate hazard ratios, relative risks, and odds ratios for anti-thyroglobuin and anti-TPO antibodies.
Outcome Measure
Additional Outcome
Lymph node metastasis, distant metastasis, recurrent disease, lymph node size and number Measures of effect We will calculate hazard ratios, relative risks, and odds ratios for anti-thyroglobuin and anti-TPO antibodies.
Study Method
Meta-analysis, Prognostic, Systematic review
Keyword
Humans; Prognosis; Thyroglobulin; Thyroid Cancer, Papillary; Thyroid Neoplasms; anti-thyroglobulin
Contact
Phillip Staibano [email protected]
Organisational Affiliation
McMaster University
Funding Source
None Grant number(s) <span style=font-size: 14px>State the funder, grant or award number and the date of award</span> None
Other Selection Criteria
Final Publication
Same Topic Review
Published Protocol
Review Type
Language
English
Country
Canada
Review Stage
Review Completed published
First Submission Date
2020-11-02
Registration Date
2020-12-02
Anticipated Start Date
2020-11-04
Anticipated Completion Date
2021-01-31
Title Cn
术前抗甲状腺球蛋白抗体和抗TPO抗体对甲状腺乳头状癌的预后效用:一项系统评价与Meta分析
Title En
Prognostic utility of preoperative anti-thyroglobulin and anti-TPO antibodies in papillary thyroid carcinoma: a systematic review and meta-analysis
Bilingual Status
complete