Meta AnalysisID 4525

慢性阻塞性肺疾病吸入糖皮质激素基础上加用茶碱:系统评价与Meta分析方案

CRD42021224952

To study the efficacy and safety of adding theophylline to ICS therapy in the treatment of COPD patients

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Record Fields

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Meta Analysis Id
4525
Evidence Id
13083
Core Evidence Id
13083
Source Meta Analysis Id
4494
Herb2 Meta Analysis Id
HBMA004494
Crd Id
CRD42021224952
Title
Adding theophylline to ICS therapy on COPD: a protocol for systematic review and meta-analysis
Review Question
To study the efficacy and safety of adding theophylline to ICS therapy in the treatment of COPD patients
Study Type Included
Any comparative study, i.e., cohort, case-control, RCTs
Condition Being Studied
Chronic obstructive pulmonary disease (COPD) is a common and frequently occurring respiratory disease. A preventable and treatable disease characterized by limited airflow, associated with abnormal inflammatory responses of the lungs to harmful particles or gases, and COPD may also affect changes in various systems throughout the body, thus having systemic effects.
Participant
Patients with chronic obstructive pulmonary disease
Animal
Human Disease Modelled
Intervention
theophylline to ICS therapy
Comparator Control
ICS therapy
Main Outcome
Severe COPD exacerbations, COPD hospital admissions, health-related quality-of-life score, total admissions, FEV1, FVC, MVV, CAT, mMRC, pneumonia, all-cause mortality, COPD-related mortality and adverse effects. Measures of effect Mean difference, odds ratio (OR) or relative risks (RR)
Outcome Measure
Additional Outcome
None Measures of effect None
Study Method
Intervention, Meta-analysis, Systematic review
Keyword
Administration, Inhalation; Humans; Meta-Analysis as Topic; Pulmonary Disease, Chronic Obstructive; Systematic Reviews as Topic; Theophylline
Contact
Lufang Feng [email protected]
Organisational Affiliation
Lanzhou university
Funding Source
No
Other Selection Criteria
Final Publication
Same Topic Review
Published Protocol
Review Type
Language
English
Country
China
Review Stage
Review Completed published
First Submission Date
2020-12-13
Registration Date
2021-01-13
Anticipated Start Date
2020-12-20
Anticipated Completion Date
2021-06-01
Title Cn
慢性阻塞性肺疾病吸入糖皮质激素基础上加用茶碱:系统评价与Meta分析方案
Title En
Adding theophylline to ICS therapy on COPD: a protocol for systematic review and meta-analysis
Bilingual Status
complete