Meta AnalysisID 4520
丹参川芎嗪注射液辅助治疗急性缺血性卒中：一项系统评价与Meta分析
CRD42022380898
This study systematically evaluated the clinical efficacy of Salviae Miltiorrhizae and Ligustrazine Hydrochloride Injection in the treatment of acute ischaemic stroke, providing a more reliable evidence-based basis for t
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Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 4520
- Evidence Id
- 13078
- Core Evidence Id
- 13078
- Source Meta Analysis Id
- 4489
- Herb2 Meta Analysis Id
- HBMA004489
- Crd Id
- CRD42022380898
- Title
- Salviae Miltiorrhizae and Ligustrazine Hydrochloride Injection as adjunctive therapy for acute ischaemic stroke: a systematic evaluation and meta-analysis
- Review Question
- This study systematically evaluated the clinical efficacy of Salviae Miltiorrhizae and Ligustrazine Hydrochloride Injection in the treatment of acute ischaemic stroke, providing a more reliable evidence-based basis for the clinical application of Tibetan Danshen Chuanxiongzin Injection.
- Study Type Included
- Clinical randomised controlled trials
- Condition Being Studied
- Ischemic stroke is the leading cause of death and disability among adults in China, characterized by high morbidity, disability, mortality, and recurrence rate.According to statistics, the age-standardized prevalence of stroke in China in 2013 was 1114.8 per 100, 000, with an incidence rate of 246.8 per 100, 000 and a mortality rate of 114.8 per 100, 000, An ongoing stroke surveillance programme covering 31 provinces in China reported an 8.3% annual increase in the incidence of first stroke in adults, from 189 per 100, 000 population in 2002 to 379 per 100, 000 population in 2013, with the incidence of ischaemic stroke and haemorrhagic stroke at 335 per 100, 000 population and 44 per 100, 000 population respectively in 2013. In the United States, more than 795, 000 people suffer a stroke each year, accounting for about one in ten deaths in the United States, and is the leading cause of long-term disability in the country . The number of people suffering from stroke is expected to increase steadily in the coming decades due to an ageing population, population growth, improved stroke care, longer life expectancy in general and an increase in the main risk factors for stroke.
- Participant
- A clinical randomised controlled trial incorporating the guideline Salviae Miltiorrhizae and Ligustrazine Hydrochloride Injection in combination with western medicine for the treatment of acute ischaemic stroke. Meet the diagnostic criteria for acute ischaemic stroke.
- Animal
- Human Disease Modelled
- Intervention
- The treatment group was treated with Salviae Miltiorrhizae and Ligustrazine Hydrochloride Injection in combination with western medicine.
- Comparator Control
- The control group was treated with the same conventional western drugs only
- Main Outcome
- Total effective rate, NIHSS score, blood rheology index, C-reactive protein, adverse reactions, etc.
- Outcome Measure
- Additional Outcome
- no
- Study Method
- Meta-analysis, Systematic review
- Keyword
- Brain Ischemia; Humans; Ischemic Stroke; Salvia miltiorrhiza; Stroke; Tibetan people; tetramethylpyrazine
- Contact
- genhao fan [email protected]
- Organisational Affiliation
- Tianjin University of Chinese Medicine
- Funding Source
- This project is supported by the Young Qihuang scholars program of National Administration of Traditional Chinese Medicine.
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- China
- Review Stage
- Review Ongoing
- First Submission Date
- 2022-12-02
- Registration Date
- 2022-12-12
- Anticipated Start Date
- 2022-12-03
- Anticipated Completion Date
- 2023-01-02
- Title Cn
- 丹参川芎嗪注射液辅助治疗急性缺血性卒中：一项系统评价与Meta分析
- Title En
- Salviae Miltiorrhizae and Ligustrazine Hydrochloride Injection as adjunctive therapy for acute ischaemic stroke: a systematic evaluation and meta-analysis
- Bilingual Status
- complete