Meta AnalysisID 4519
川芎嗪注射液治疗妊娠期高血压疾病的疗效与安全性：一项Meta分析
CRD42022334460
Efficacy and safety of ligustrazine injection in the treatment of hypertensive disease during pregnancy: a meta-analysis
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Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 4519
- Evidence Id
- 13077
- Core Evidence Id
- 13077
- Source Meta Analysis Id
- 4488
- Herb2 Meta Analysis Id
- HBMA004488
- Crd Id
- CRD42022334460
- Title
- Efficacy and safety of ligustrazine injection in the treatment of hypertensive disease during pregnancy: a meta-analysis
- Review Question
- Efficacy and safety of ligustrazine injection in the treatment of hypertensive disease during pregnancy: a meta-analysis
- Study Type Included
- Domestic and foreign published randomized controlled trial (RCTS) of ligustrazine injection in the treatment of hypertension in pregnancy. Restricted languages are Chinese and English.
- Condition Being Studied
- Gestational hypertension is a disease that affects 5% to 10% of pregnant women worldwide and is associated with adverse fetal, neonatal and maternal outcomes such as placental abruption, premature delivery, stroke, disseminated intravascular coagulation and multiple organ (liver and kidney) failure, as well as adverse long-term cardiovascular health of women. Preexisting hypertension, gestational hypertension, preeclampsia, eclampsia, and HELLP syndrome. Ligusticum Chuanxiong, as a common medicinal and edible herb, has an ideal therapeutic effect on cardiovascular and cerebrovascular diseases. This paper makes a systematic evaluation of ligustrazine in treating hypertensive disorder complicating pregnancy by meta-analysis, in order to provide evidence-based medical evidence for clinic.
- Participant
- Patients who meet the recognized diagnostic criteria for gestational hypertension are of no age or nationality.
- Animal
- Human Disease Modelled
- Intervention
- The experimental group was given ligustrazine injection alone or on the basis of the control group.
- Comparator Control
- The control group was given conventional western medicine alone.
- Main Outcome
- The total curative effect、Effects on mother and child、adverse reactions Measures of effect 总体疗效; 对母婴的影响
- Outcome Measure
- Additional Outcome
- None 没有
- Study Method
- Meta-analysis, Systematic review
- Keyword
- Drugs, Chinese Herbal; Female; Humans; Hypertension; Pregnancy; Pyrazines; tetramethylpyrazine
- Contact
- Kefei Wang [email protected]
- Organisational Affiliation
- Shandong University of Traditional Chinese Medicine
- Funding Source
- None 没有
- Other Selection Criteria
- Final Publication
- Same Topic Review
- None 没有
- Published Protocol
- Review Type
- Language
- English
- Country
- China
- Review Stage
- Review Ongoing
- First Submission Date
- 2022-05-23
- Registration Date
- 2022-06-03
- Anticipated Start Date
- 2022-04-20
- Anticipated Completion Date
- 2022-06-30
- Title Cn
- 川芎嗪注射液治疗妊娠期高血压疾病的疗效与安全性：一项Meta分析
- Title En
- Efficacy and safety of ligustrazine injection in the treatment of hypertensive disease during pregnancy: a meta-analysis
- Bilingual Status
- complete