Meta AnalysisID 4512
丹参酮联合川芎嗪治疗稳定型心绞痛的临床疗效：系统评价与Meta分析
CRD42018105921
For the treatment of stable angina, many clinical trials have reported the beneficial effects of tanshinol combined with ligustrazine. Considering no relevant systematic reviews have assessed the clinical efficacy or the
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Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 4512
- Evidence Id
- 13070
- Core Evidence Id
- 13070
- Source Meta Analysis Id
- 4482
- Herb2 Meta Analysis Id
- HBMA004482
- Crd Id
- CRD42018105921
- Title
- The clinical efficacy of tanshinol combined with ligustrazine in the treatment of stable angina: a systematic review and meta-analysis
- Review Question
- For the treatment of stable angina, many clinical trials have reported the beneficial effects of tanshinol combined with ligustrazine. Considering no relevant systematic reviews have assessed the clinical efficacy or the risk, in this study, a meta-analysis was conducted to evaluate the efficacy of tanshinol combined with ligustrazine in the treatment of stable angina.
- Study Type Included
- Only randomized controlled trials (RCTs) will be included. Observational, cohort, case-control, case series, qualitative and laboratory studies, and uncontrolled trials will be excluded.
- Condition Being Studied
- Stable angina refers to the classic type of angina related to myocardial ischemia. It is caused by a stable plaque that has not ruptured, but instead is producing a partial, fixed blockage in a coronary artery. This meta-analysis seeks to assess the effectiveness and safety of tanshinol combined with ligustrazine in the treatment of stable angina.
- Participant
- Patients who were diagnosed with stable angina were included. The stable angina was diagnosed according to the criteria, with tests such as electrocardiography (ECG), exercise ECG, and symptoms of the patients.
- Animal
- Human Disease Modelled
- Intervention
- Interventions using tanshinol combined with ligustrazine as a main treatment were chosen. The dosages of tanshinol and ligustrazine should be described specifically.
- Comparator Control
- The control groups received conventional treatments, such as taking medicines to treat and prevent angina attacks. Placeboes were also included.
- Main Outcome
- The clinical efficacy in symptoms and ECG. Measures of effect Not applicable.
- Outcome Measure
- Additional Outcome
- Adverse events. Measures of effect Not applicable.
- Study Method
- Meta-analysis, Systematic review
- Keyword
- 3, 4-dihydroxyphenyllactic acid; Angina, Stable; Humans; Lactates; Pyrazines; Treatment Outcome; tetramethylpyrazine
- Contact
- Li Gao [email protected]
- Organisational Affiliation
- Beijing University of Chinese Medicine http://www.bucm.edu.cn/
- Funding Source
- This study was supported by China Postdoctoral Science Foundation (Grant No. 2019M650598), Fundamental Research Funds for the Central Universities (Grant No. 2019-JYB-JS-005), National Natural Science Foundation of China (Grant No. 81874514), and National Key Research and Development Program of China (Grant No. 2017YFC1700102).
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- China
- Review Stage
- Review Completed not published
- First Submission Date
- 2018-08-02
- Registration Date
- 2018-08-17
- Anticipated Start Date
- 2018-05-20
- Anticipated Completion Date
- 2019-05-30
- Title Cn
- 丹参酮联合川芎嗪治疗稳定型心绞痛的临床疗效：系统评价与Meta分析
- Title En
- The clinical efficacy of tanshinol combined with ligustrazine in the treatment of stable angina: a systematic review and meta-analysis
- Bilingual Status
- complete