Meta AnalysisID 438

草药治疗口腔扁平苔藓的疗效如何?

CRD42022358043

The main objective of this systematic review and meta analysis is to determine what is the efficacy of herbal medications in oral lichen planus .

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Record Fields

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Meta Analysis Id
438
Evidence Id
8996
Core Evidence Id
8996
Source Meta Analysis Id
415
Herb2 Meta Analysis Id
HBMA000415
Crd Id
CRD42022358043
Title
what is the efficacy of herbal medications in oral lichen planus .
Review Question
The main objective of this systematic review and meta analysis is to determine what is the efficacy of herbal medications in oral lichen planus .
Study Type Included
Randomised clinical trials will be included .case reports, case series, letter to the editors, abstracts will be excluded.
Condition Being Studied
Lichen planus is an inflammatory, autoimmune disease that can affect the skin as well as the mucous membranes. Mucosa lesions in OLP are chronic, rarely undergo spontaneous remission, are potentially premalignant even leading to oral cancer. Numerous new methods and treatments have been available and provided a variety of treatment options, including topical steroids, immunosuppressant, retinoid, Nutraceuticals, phototherapy, Photodynamic therapy and surgery.
Participant
Patients with signs and symptoms of Oral Iichen planus and also confirmed by histopathology.
Animal
Human Disease Modelled
Intervention
Administration of herbal medications in oral lichen planus like aloe vera, curcumin , Glycyrizha glabra purslane, chinese medicine, lycopene , raspberry leaf extract e.t.c
Comparator Control
Numerous new methods and treatments are available, but the comparator will be any other treatment modality(corticosteroids, tacrolimus, calcineurin inhibitors).
Main Outcome
Sign score for the clinical improvement was scored according to criteria set by Thongprasom et al.
Outcome Measure
Additional Outcome
Levels of anxiety , salivary cortisol , HCV -Seropositivity , diabetes mellitus , hypertension , thyroid dysfunction , TNF-alpha , kappa B, Cell surface receptors(CCR1, CCR3, CCR4, CCR5, CCR9, CCR10).
Study Method
Systematic review
Keyword
Humans; Lichen Planus, Oral
Contact
Reshu Rastogi [email protected]
Organisational Affiliation
Kothiwal dental college hospital and research centre
Funding Source
Other Selection Criteria
Final Publication
Same Topic Review
Published Protocol
Review Type
Language
English
Country
India
Review Stage
Review Ongoing
First Submission Date
2022-09-04
Registration Date
2022-09-15
Anticipated Start Date
2022-09-10
Anticipated Completion Date
2023-03-10
Title Cn
草药治疗口腔扁平苔藓的疗效如何?
Title En
what is the efficacy of herbal medications in oral lichen planus .
Bilingual Status
complete