Meta AnalysisID 4357
食物结构和抗性淀粉对2型糖尿病或糖尿病前期个体血糖反应的影响
CRD42021233918
Will the current studies completed in type 2 diabetics provide any insight on to the effect of food structure and resistant starch (supplements and naturally sourced) on markers of glycaemic control and insulin sensitivi
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Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 4357
- Evidence Id
- 12915
- Core Evidence Id
- 12915
- Source Meta Analysis Id
- 4324
- Herb2 Meta Analysis Id
- HBMA004324
- Crd Id
- CRD42021233918
- Title
- The impact of food structures and resistant starch on glycaemic response in individuals with type II diabetes or pre-diabetes
- Review Question
- Will the current studies completed in type 2 diabetics provide any insight on to the effect of food structure and resistant starch (supplements and naturally sourced) on markers of glycaemic control and insulin sensitivity?
- Study Type Included
- Crossover RCT
- Condition Being Studied
- Type 2 diabetics or pre-diabetics
- Participant
- Inclusion: Adults, >18 years old, diagnosed with type 2 diabetes and pre-diabetes (as diagnosed by any diagnostic criteria) Excludes: type 2 diabetics with other chronic conditions (nephropathy, liver failure, coronary heart disease)
- Animal
- Human Disease Modelled
- Intervention
- Resistant starch Type 1 – 5, intact food structures
- Comparator Control
- Starch/other carbohydrate (non-resistant), processed food structures (via food processing, preparation, mastication)
- Main Outcome
- Glycaemia markers (glucose /Insulin/HOMA/HbA1C) Measures of effect Mean fasting concentrations of glucose and insulin Measures of insulin sensitivity (HOMA-IR, Matusuda) Changes in HbA1c level Glucose and insulin incremental area under curve (iAUC)
- Outcome Measure
- Additional Outcome
- Side effects and gastrointestinal tolerability Satiety Changes in weight or Body mass index (BMI) Measures of effect Percentage of participants experiencing side effects or changes in gastrointestinal symptoms Satiety measured through gut hormone concentrations, ad-libitum meal energy intake or Visual analogue scales of satiety Changes in BMI (kg/m^2) or weight (kg)
- Study Method
- Meta-analysis, Systematic review
- Keyword
- Diabetes Mellitus, Type 2; Diet; Food; Humans; Prediabetic State; Resistant Starch
- Contact
- Jennifer Pugh [email protected]
- Organisational Affiliation
- Imperial College London https://www.imperial.ac.uk/
- Funding Source
- Imperial College London
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- England
- Review Stage
- Review Ongoing
- First Submission Date
- 2021-01-28
- Registration Date
- 2021-02-01
- Anticipated Start Date
- 2021-01-15
- Anticipated Completion Date
- 2022-11-30
- Title Cn
- 食物结构和抗性淀粉对2型糖尿病或糖尿病前期个体血糖反应的影响
- Title En
- The impact of food structures and resistant starch on glycaemic response in individuals with type II diabetes or pre-diabetes
- Bilingual Status
- complete