Meta AnalysisID 4352
羟乙基淀粉与晶体液对腹部大手术患者急性肾损伤影响的比较：一项系统评价与Meta分析及试验序贯分析
CRD42020163450
Does the intra-operative use of hydroethyl starch increases stage 1 acute kidney injury in patients undergoing major abdominal surgery, compared to crystalloid?
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Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 4352
- Evidence Id
- 12910
- Core Evidence Id
- 12910
- Source Meta Analysis Id
- 4319
- Herb2 Meta Analysis Id
- HBMA004319
- Crd Id
- CRD42020163450
- Title
- Hydroxyethyl starch versus crystalloid on acute kidney injury in patients undergoing major abdominal surgery : a systematic review with meta-analysis and trial sequential analysis
- Review Question
- Does the intra-operative use of hydroethyl starch increases stage 1 acute kidney injury in patients undergoing major abdominal surgery, compared to crystalloid?
- Study Type Included
- Randomized controlled trials
- Condition Being Studied
- <b>Major abdominal surgery is defined as an open or laparoscopic-assisted abdominal surgery expected to last at least 2 hours. </b>
- Participant
- - Patients undergoing major abdominal surgery, defined as open or laparoscopic-assisted abdominal surgery expected to last at least 2 hours. - Over 18 years old
- Animal
- Human Disease Modelled
- Intervention
- Intraoperative infusion of hydroxyethyl starch
- Comparator Control
- Intraoperative infusion of crystalloid fluids alone
- Main Outcome
- The main outcome will be 30-day acute kidney injury, defined according to the KDIGO guidelines Measures of effect number of events at day-30
- Outcome Measure
- Additional Outcome
- - Stage 1 acute kidney injury at day 30 - Need for renal remplacement therapy at day 30 - Incidence of a post-operative complication within 30 days (defined as anastomotic leakage, intra-abdominal sepsis or reoperation) - Anastomotic leakage within 30 days - Intra-operative transfusion of blood products - Intra-operative blood loss - Need for intra-operative use of norepinephrine - Intra-operative fluid balance - Mortality at day 30 Measures of effect number of events or ml at day-30 or intra-operative according to the outcome
- Study Method
- Intervention, Meta-analysis, Systematic review
- Keyword
- Humans
- Contact
- Samir Jaber [email protected]
- Organisational Affiliation
- CHU Montpellier, France
- Funding Source
- Other Selection Criteria
- Final Publication
- Pensier J, Deffontis L, Rollé A, et al. Hydroxyethyl starch for fluid management in patients undergoing major abdominal surgery: a systematic review with meta-analysis and trial sequential analysis. Anesth Analg. 2022;134:686–695. https://journals-lww-com.ezpum.scdi-montpellier.fr/anesthesia-analgesia/Fulltext/2022/04000/Hydroxyethyl_Starch_for_Fluid_Management_in.8.aspx
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- France
- Review Stage
- Review Completed published
- First Submission Date
- 2020-01-02
- Registration Date
- 2020-04-28
- Anticipated Start Date
- 2019-11-01
- Anticipated Completion Date
- 2020-02-01
- Title Cn
- 羟乙基淀粉与晶体液对腹部大手术患者急性肾损伤影响的比较：一项系统评价与Meta分析及试验序贯分析
- Title En
- Hydroxyethyl starch versus crystalloid on acute kidney injury in patients undergoing major abdominal surgery : a systematic review with meta-analysis and trial sequential analysis
- Bilingual Status
- complete