Meta AnalysisID 4338

使用添加植物甾醇和甾烷醇的食品改善低密度脂蛋白胆固醇水平:一项系统评价与Meta分析

CRD42021236952

What is the LDL cholesterol reduction with plant sterol and stanol fortified food? Is LDL cholesterol reduction with phytosterols altered by: 1. Type of fortified food: milk and yoghurt / butter, margarine and spreads /

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Record Fields

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Meta Analysis Id
4338
Evidence Id
12896
Core Evidence Id
12896
Source Meta Analysis Id
4304
Herb2 Meta Analysis Id
HBMA004304
Crd Id
CRD42021236952
Title
Use of plant sterol and stanol fortified foods to improve the LDL cholesterol level: a systematic review and meta-analysis
Review Question
What is the LDL cholesterol reduction with plant sterol and stanol fortified food? Is LDL cholesterol reduction with phytosterols altered by: 1. Type of fortified food: milk and yoghurt / butter, margarine and spreads / cheese / sauces / drinks / other 2. Intervention time: ≤ 1 month / 1 to 3 months / ≥ 3 months 3. Intervention dose: <2g of plant sterol or stanol per day / 2-2.5g / >2.5g) 4. Concomitant medication: Use or not of concomitant treatment with statins 5. Intake pattern: a) In one dose or the same dose in separated intakes b) Fixed in main meals (breakfast, lunch and/or dinner) or free election of any meal of the day, main or not
Study Type Included
Randomized controlled trials (RCTs), controlled clinical trials (CCTs)
Condition Being Studied
LDL cholesterol concentration
Participant
Adult populations only (>18 y old) Exclusion: non human.
Animal
Human Disease Modelled
Intervention
Intervention: Plant sterol and stanol fortified foods Inclusion criteria: 1. Randomized controlled trials (RCTs) and controlled clinical trials (CCTs) with placebo as control group Exclusion: 1. Non human 2. <18 years old
Comparator Control
placebo
Main Outcome
LDL cholesterol change versus placebo Measures of effect LDL cholesterol change versus placebo
Outcome Measure
Additional Outcome
None Measures of effect none
Study Method
Meta-analysis, Systematic review
Keyword
Cholesterol, LDL; Food, Fortified; Humans; Phytosterols; Sitosterols
Contact
David Benaiges [email protected]
Organisational Affiliation
Hospital del Mar
Funding Source
Other Selection Criteria
Final Publication
Same Topic Review
Published Protocol
Review Type
Language
English
Country
Spain
Review Stage
Review Ongoing
First Submission Date
2021-03-05
Registration Date
2021-04-05
Anticipated Start Date
2021-03-01
Anticipated Completion Date
2022-04-01
Title Cn
使用添加植物甾醇和甾烷醇的食品改善低密度脂蛋白胆固醇水平:一项系统评价与Meta分析
Title En
Use of plant sterol and stanol fortified foods to improve the LDL cholesterol level: a systematic review and meta-analysis
Bilingual Status
complete