Meta AnalysisID 4335
丹参酮IIA磺酸钠注射液对急性冠脉综合征患者血脂的影响：随机临床试验的系统评价与Meta分析
CRD42023391492
The purpose of this study was to systematically review the effects of Sodium Tanshinone IIA Sulfonate injection (STS) on blood lipid in patients with acute coronary syndrome (ACS), so as to provide evidence for further r
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Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 4335
- Evidence Id
- 12893
- Core Evidence Id
- 12893
- Source Meta Analysis Id
- 4302
- Herb2 Meta Analysis Id
- HBMA004302
- Crd Id
- CRD42023391492
- Title
- Effects of Sodium Tanshinone IIA Sulfonate Injection on Blood Lipid in Patients with Acute Coronary Syndrome: A Systematic Review and Meta-Analysis of Randomized Clinical Trials
- Review Question
- The purpose of this study was to systematically review the effects of Sodium Tanshinone IIA Sulfonate injection (STS) on blood lipid in patients with acute coronary syndrome (ACS), so as to provide evidence for further research.
- Study Type Included
- Randomized controlled trials (RCT)
- Condition Being Studied
- Acute coronary syndrome (ACS) is a common disease of the cardiovascular system characterized by acute myocardial ischemia caused by disruption of coronary artery plaque and consequent thrombosis-induced severe coronary artery stenosis or occlusion, including acute ST-segment elevation myocardial infarction (STEMI), acute non-ST-segment elevation myocardial infarction (NSTEMI) and unstable angina (UAP). Dyslipidemia is closely related to the occurrence and progression of coronary atherosclerosis and cardiovascular events. An increasing number of controlled clinical studies have found that Sodium Tanshinone IIA Sulfonate injection (STS) is effective in ACS and improves patients' blood lipid profile. However, meta-analysis of the effects of STS on blood lipids remains less. Therefore, we evaluated the effect of STS on blood lipid in ACS patients through a meta-analysis system.
- Participant
- Patients of any age and sex who meet established diagnostic criteria for ACS
- Animal
- Human Disease Modelled
- Intervention
- conventional therapy in addition to Sodium Tanshinone IIA Sulfonate injection
- Comparator Control
- conventional therapy
- Main Outcome
- Any lipid profile parameters, including total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), triglycerides (TG) and high-density lipoprotein cholesterol (HDL-C); frequencies of adverse events.
- Outcome Measure
- Additional Outcome
- Study Method
- Systematic review
- Keyword
- Acute Coronary Syndrome; Humans; Lipids; Phenanthrenes; Randomized Controlled Trials as Topic; tanshinone II A sodium sulfonate
- Contact
- Zunqi Kan [email protected]
- Organisational Affiliation
- Shandong University of Traditional Chinese Medicine
- Funding Source
- This research was supported by the National Key R&D Program “Research on the Modernization of Traditional Chinese Medicine” Key Special Projects (2017YFC1702700).
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- China
- Review Stage
- Review Ongoing
- First Submission Date
- 2023-01-13
- Registration Date
- 2023-01-23
- Anticipated Start Date
- 2023-01-11
- Anticipated Completion Date
- 2023-04-30
- Title Cn
- 丹参酮IIA磺酸钠注射液对急性冠脉综合征患者血脂的影响：随机临床试验的系统评价与Meta分析
- Title En
- Effects of Sodium Tanshinone IIA Sulfonate Injection on Blood Lipid in Patients with Acute Coronary Syndrome: A Systematic Review and Meta-Analysis of Randomized Clinical Trials
- Bilingual Status
- complete