Meta AnalysisID 4333
膳食钠与非酒精性脂肪性肝病：一项系统评价
CRD42023390447
The objective of this review is to compile and critically analyze research in humans and animals that verified the influence of different patterns of sodium consumption on NAFLD markers.
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Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 4333
- Evidence Id
- 12891
- Core Evidence Id
- 12891
- Source Meta Analysis Id
- 4300
- Herb2 Meta Analysis Id
- HBMA004300
- Crd Id
- CRD42023390447
- Title
- Dietary Sodium and nonalcoholic fatty liver disease: a systematic review
- Review Question
- The objective of this review is to compile and critically analyze research in humans and animals that verified the influence of different patterns of sodium consumption on NAFLD markers.
- Study Type Included
- There are no restriction on the type of study
- Condition Being Studied
- Nonalcoholic Fatty Liver Disease
- Participant
- The studies could be in humans (without the restriction of the population studied) or experimental animals.
- Animal
- Human Disease Modelled
- Intervention
- The studies should compare the prevalence/incidence of NAFLD, or, if intervention, the alteration of steatosis or fibrosis markers in the liver tissue according to sodium intake. In humans, sodium consumption should have been assessed bya food frequency questionnaire, 24-hour recall, 24-hour urine collection, or urine collection < 24 hours. NAFLD should have been assessed by biopsy, FIBROSCAN, ultrasound, or validated formulas. Those studies that reported only the dietary pattern of people with NAFLD without correction for con-founding factors, even though sodium intake was compared between cases and control, were not selected.
- Comparator Control
- People/animals fed normal or low-sodium intake
- Main Outcome
- The prevalence/incidence of NAFLD, or, if intervention, the alteration of steatosis and/or fibrosis markers in the liver according to sodium intake in humans. Steatosis markers in experimental animals. Measures of effect Odds ratio, Hazard ratio
- Outcome Measure
- Additional Outcome
- Not applicable
- Study Method
- Narrative synthesis, Systematic review
- Keyword
- Animals; Diet; Humans; Non-alcoholic Fatty Liver Disease; Sodium; Sodium Chloride, Dietary; Sodium, Dietary
- Contact
- Guilherme Ferreira [email protected]
- Organisational Affiliation
- Laboratorio de Lípides (LIM 10) do Hospital das Clínicas (HCFMUSP) da Faculdade de Medicina da Universidade de Sao Paulo
- Funding Source
- Fundação de Amparo à Pesquisa do Estado de São Paulo, FAPESP, (#2016/15603-0 to MP), and Coordenação de Aperfeiçoamento de Pessoal de Nível Superior – Brasil (CAPES; 001, to GSF), and Conselho Nacional de Desenvolvimento Científico e Tecnológico, CNPq (to MP), Brazil. Grant number(s) <span style=font-size: 14px>State the funder, grant or award number and the date of award</span> FAPESP, (#2016/15603-0 to MP); CAPES (# 001 to GSF)
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English, Portuguese-Brazil
- Country
- Brazil
- Review Stage
- Review Ongoing
- First Submission Date
- 2023-01-09
- Registration Date
- 2023-01-20
- Anticipated Start Date
- 2021-06-01
- Anticipated Completion Date
- 2023-02-07
- Title Cn
- 膳食钠与非酒精性脂肪性肝病：一项系统评价
- Title En
- Dietary Sodium and nonalcoholic fatty liver disease: a systematic review
- Bilingual Status
- complete