Meta AnalysisID 4327
丹参酮IIA磺酸钠注射液对冠心病患者血管内皮功能和炎症因子的影响:随机临床试验的系统评价和Meta分析
CRD42022336006
P: Patients with coronary heart disease; 1: Tanshinone group treated with tanshinone IIA sodium sulfonate injection and conventional western medicine; C: The control group treated with the same basic Western medicine as
Relationship Network
Interactive first-hop connections across herbs, ingredients, formulas, targets, diseases, symptoms, syndromes, evidence, and monographs.
Click a node to open it in a new tab
Ingredient: 1Meta-analysis: 1Links: 1
Arranging relationship network...
Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 4327
- Evidence Id
- 12885
- Core Evidence Id
- 12885
- Source Meta Analysis Id
- 4295
- Herb2 Meta Analysis Id
- HBMA004295
- Crd Id
- CRD42022336006
- Title
- Effects of tanshinone IIA sulfonate sodium injection on vascular endothelial function and inflammatory factors in patients with coronary heart disease: a systematic review and meta-analysis of randomized clinical trials
- Review Question
- P: Patients with coronary heart disease; 1: Tanshinone group treated with tanshinone IIA sodium sulfonate injection and conventional western medicine; C: The control group treated with the same basic Western medicine as tanshinone group; O: Related factors reflecting inflammatory response and endothelial function; S: Randomized controlled study
- Study Type Included
- Randomized controlled study
- Condition Being Studied
- Cardiovascular diseases (CVDs) are the primary cause of mortality worldwide causing 17.3 million deaths per year, and the number is estimated to reach 23.6 million in 2030, making it a critical issue for the public health system.
- Participant
- Patients, of any age and gender, with coronary heart disease, diagnosed according to established diagnostic criteria.
- Animal
- Human Disease Modelled
- Intervention
- conventional therapy in addition to sodium Tanshinone IIA sulfonate injection
- Comparator Control
- conventional therapy
- Main Outcome
- Factors related to inflammatory response and endothelial function, including CRP , IL-6, TNF- α, Effects of MMP-9, NO, Hcy , ET-1; frequencies of adverse events.
- Outcome Measure
- Additional Outcome
- Study Method
- Meta-analysis, Systematic review
- Keyword
- Coronary Disease; Humans; Phenanthrenes; Randomized Controlled Trials as Topic; Sodium; tanshinone II A sodium sulfonate
- Contact
- Ruixiang Kang [email protected]
- Organisational Affiliation
- Shandong University of traditional Chinese medicine https://www.sdutcm.edu.cn/
- Funding Source
- none Grant number(s) <span style=font-size: 14px>State the funder, grant or award number and the date of award</span> none
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- China
- Review Stage
- Review Ongoing
- First Submission Date
- 2022-05-28
- Registration Date
- 2022-06-08
- Anticipated Start Date
- 2022-03-01
- Anticipated Completion Date
- 2022-06-30
- Title Cn
- 丹参酮IIA磺酸钠注射液对冠心病患者血管内皮功能和炎症因子的影响:随机临床试验的系统评价和Meta分析
- Title En
- Effects of tanshinone IIA sulfonate sodium injection on vascular endothelial function and inflammatory factors in patients with coronary heart disease: a systematic review and meta-analysis of randomized clinical trials
- Bilingual Status
- complete