Meta AnalysisID 4327

丹参酮IIA磺酸钠注射液对冠心病患者血管内皮功能和炎症因子的影响:随机临床试验的系统评价和Meta分析

CRD42022336006

P: Patients with coronary heart disease; 1: Tanshinone group treated with tanshinone IIA sodium sulfonate injection and conventional western medicine; C: The control group treated with the same basic Western medicine as

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Record Fields

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Meta Analysis Id
4327
Evidence Id
12885
Core Evidence Id
12885
Source Meta Analysis Id
4295
Herb2 Meta Analysis Id
HBMA004295
Crd Id
CRD42022336006
Title
Effects of tanshinone IIA sulfonate sodium injection on vascular endothelial function and inflammatory factors in patients with coronary heart disease: a systematic review and meta-analysis of randomized clinical trials
Review Question
P: Patients with coronary heart disease; 1: Tanshinone group treated with tanshinone IIA sodium sulfonate injection and conventional western medicine; C: The control group treated with the same basic Western medicine as tanshinone group; O: Related factors reflecting inflammatory response and endothelial function; S: Randomized controlled study
Study Type Included
Randomized controlled study
Condition Being Studied
Cardiovascular diseases (CVDs) are the primary cause of mortality worldwide causing 17.3 million deaths per year, and the number is estimated to reach 23.6 million in 2030, making it a critical issue for the public health system.
Participant
Patients, of any age and gender, with coronary heart disease, diagnosed according to established diagnostic criteria.
Animal
Human Disease Modelled
Intervention
conventional therapy in addition to sodium Tanshinone IIA sulfonate injection
Comparator Control
conventional therapy
Main Outcome
Factors related to inflammatory response and endothelial function, including CRP , IL-6, TNF- α, Effects of MMP-9, NO, Hcy , ET-1; frequencies of adverse events.
Outcome Measure
Additional Outcome
Study Method
Meta-analysis, Systematic review
Keyword
Coronary Disease; Humans; Phenanthrenes; Randomized Controlled Trials as Topic; Sodium; tanshinone II A sodium sulfonate
Contact
Ruixiang Kang [email protected]
Organisational Affiliation
Shandong University of traditional Chinese medicine https://www.sdutcm.edu.cn/
Funding Source
none Grant number(s) <span style=font-size: 14px>State the funder, grant or award number and the date of award</span> none
Other Selection Criteria
Final Publication
Same Topic Review
Published Protocol
Review Type
Language
English
Country
China
Review Stage
Review Ongoing
First Submission Date
2022-05-28
Registration Date
2022-06-08
Anticipated Start Date
2022-03-01
Anticipated Completion Date
2022-06-30
Title Cn
丹参酮IIA磺酸钠注射液对冠心病患者血管内皮功能和炎症因子的影响:随机临床试验的系统评价和Meta分析
Title En
Effects of tanshinone IIA sulfonate sodium injection on vascular endothelial function and inflammatory factors in patients with coronary heart disease: a systematic review and meta-analysis of randomized clinical trials
Bilingual Status
complete