Meta AnalysisID 4324
宫内暴露于丙戊酸钠对神经心理学结局的系统评价
CRD42022328658
What are the neuropsychological outcomes associated with in utero exposure to sodium valproate?
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Record Fields
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- Meta Analysis Id
- 4324
- Evidence Id
- 12882
- Core Evidence Id
- 12882
- Source Meta Analysis Id
- 4293
- Herb2 Meta Analysis Id
- HBMA004293
- Crd Id
- CRD42022328658
- Title
- A Systematic Review of Neuropsychological Outcomes of in Utero Exposure to Sodium Valproate
- Review Question
- What are the neuropsychological outcomes associated with in utero exposure to sodium valproate?
- Study Type Included
- Inclusion criteria: Primary research papers published in peer-reviewed journals investigating neuropsychological outcomes (e.g., IQ, adaptive behaviour, frequency of neurodevelopmental disorders) in children and young people exposed in utero to sodium valproate. Limitations on the inclusion criteria: 1. Human participants, 2. Published in English.
- Condition Being Studied
- Exposure to sodium valproate in utero.
- Participant
- Human participants of all ages who have been exposed to sodium valproate in utero.
- Animal
- Human Disease Modelled
- Intervention
- Exposure to sodium valproate in utero.
- Comparator Control
- Children of mothers who did not take sodium valproate during pregnancy.
- Main Outcome
- Global cognitive outcomes (e.g., IQ, DQ, presence of Learning Disability) Measures of effect Not applicable
- Outcome Measure
- Additional Outcome
- • Specific cognitive outcomes (e.g., memory, attention, language) • Other outcomes, including estimates of functional outcomes (e.g., adaptive functioning, academic attainment) and signals of atypical neurodevelopment (e.g., incidence and/or traits of ASD, ADHD, developmental delay). Measures of effect Not applicable
- Study Method
- Meta-analysis, Narrative synthesis, Systematic review
- Keyword
- Humans; Valproic Acid
- Contact
- Kurt Armstrong [email protected]
- Organisational Affiliation
- The University of Manchester https://www.manchester.ac.uk/
- Funding Source
- Not applicable Grant number(s) <span style=font-size: 14px>State the funder, grant or award number and the date of award</span> Not applicable
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Not applicable
- Published Protocol
- Review Type
- Language
- English
- Country
- England
- Review Stage
- Review Ongoing
- First Submission Date
- 2022-04-27
- Registration Date
- 2022-04-29
- Anticipated Start Date
- 2022-05-02
- Anticipated Completion Date
- 2022-09-02
- Title Cn
- 宫内暴露于丙戊酸钠对神经心理学结局的系统评价
- Title En
- A Systematic Review of Neuropsychological Outcomes of in Utero Exposure to Sodium Valproate
- Bilingual Status
- complete