Meta AnalysisID 4322

心力衰竭患者中限制钠摄入与高钠摄入或常规护理的比较

CRD42022326954

1. What is the effect of sodium or salt restriction on the outcome of all-cause mortality in patients with heart failure? 2. What is the effect of sodium or salt restriction on the outcome of all-cause, cardiovascular-re

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Record Fields

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Meta Analysis Id
4322
Evidence Id
12880
Core Evidence Id
12880
Source Meta Analysis Id
4291
Herb2 Meta Analysis Id
HBMA004291
Crd Id
CRD42022326954
Title
Sodium Restriction versus High Sodium Intake or Usual Care in Heart Failure
Review Question
1. What is the effect of sodium or salt restriction on the outcome of all-cause mortality in patients with heart failure? 2. What is the effect of sodium or salt restriction on the outcome of all-cause, cardiovascular-related, and heart failure-related hospitalization in patients with heart failure? 3. What is the effect of sodium or salt restriction on the composite outcome of death and rehospitalization in patients with heart failure? 4. Does sodium or salt restriction have differential effects on clinical outcomes including all-cause death and hospitalization in different subgroups from inpatient versus outpatient setting, HFrEF versus HFpEF patient populations, different intensities of salt restriction, or different durations of intervention/follow-up?
Study Type Included
RCTs
Condition Being Studied
Heart Failure, including all subtypes (HFrEF, HFmrEF, and HFpEF), both inpatient and outpatient settings
Participant
Heart failure patients with ≥ 18 years old, from both inpatient and outpatient settings
Animal
Human Disease Modelled
Intervention
Sodium or Salt restriction
Comparator Control
No Sodium or Salt restriction or less strict salt restriction regimens
Main Outcome
Primary outcome of interest: all-cause mortality Measures of effect Odds Ratio (95% confidence interval)
Outcome Measure
Additional Outcome
Secondary outcomes: all-cause, cardiovascular-related and heart failure-related hospitalization, adverse events, length of inpatient stay, change in New York Heart Association [NYHA] functional class, change in Quality of Life measures, adherence to dietary low-salt intake, and changes in blood pressure Measures of effect Odds Ratio or Mean Difference, as appropriate
Study Method
Meta-analysis, Prognostic, Systematic review
Keyword
Blood Pressure; Diet, Sodium-Restricted; Heart Failure; Humans; Sodium; Sodium, Dietary
Contact
Nariman Sepehrvand [email protected]
Organisational Affiliation
University of Alberta https://thecvc.ca/
Funding Source
Not applicable
Other Selection Criteria
Final Publication
Same Topic Review
Published Protocol
Review Type
Language
English
Country
Canada, Mexico
Review Stage
Review Ongoing
First Submission Date
2022-04-20
Registration Date
2022-05-10
Anticipated Start Date
2022-04-02
Anticipated Completion Date
2022-05-31
Title Cn
心力衰竭患者中限制钠摄入与高钠摄入或常规护理的比较
Title En
Sodium Restriction versus High Sodium Intake or Usual Care in Heart Failure
Bilingual Status
complete