Meta AnalysisID 422
可可对代谢综合征结局的影响：系统评价与Meta分析
CRD42023388210
What is the effect of cocoa consumption on metabolic syndrome outcomes?
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Record Fields
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- Meta Analysis Id
- 422
- Evidence Id
- 8980
- Core Evidence Id
- 8980
- Source Meta Analysis Id
- 400
- Herb2 Meta Analysis Id
- HBMA000400
- Crd Id
- CRD42023388210
- Title
- Effect of Cocoa on Metabolic Syndrome Outcomes: A Systematic Review and Meta-Analysis
- Review Question
- What is the effect of cocoa consumption on metabolic syndrome outcomes?
- Study Type Included
- We will include randomised-controlled trials (both parallel and cross-over study design) to measure the effect of cocoa on metabolic syndrome outcomes.
- Condition Being Studied
- This review will focus on metabolic syndrome parameters as main outcomes. The outcomes are: 1) Blood glucose 2) Systolic blood pressure (SBP) 3) Diastolic blood pressure (DBP) 4) LDL-c levels 5) HDL-c levels
- Participant
- This study will involve free-living men and women (aged from 18 to 75 years) with metabolic syndrome defined as having three or more of the following conditions: 1) waist circumference over 40 inches (men) or 35 inches (women) 2) blood pressure over 130/85 mmHg 3) fasting triglyceride (TG) level over 150 mg/dL 4) fasting high-density lipoprotein (HDL) cholesterol level less than 40 mg/dL (men) or 50 mg/dL (women) 5) fasting blood sugar over 100 mg/dL The inclusion criteria are who did not take any medications, vitamins, and/or supplements during the study period. The exclusion criteria are those with dietary restrictions or medical conditions other than metabolic syndrome and women who are pregnant, or lactating were excluded.
- Animal
- Human Disease Modelled
- Intervention
- This review will include the following interventions: 1) Cocoa 2) Cocoa powder 3) Low and high flavanols cocoa 4) Dark chocolate 5) Polyphenol-rich dark chocolate The intake of the product can be either in the form of liquid, semi-solid, and solid.
- Comparator Control
- The appropriate control/comparators(s) should be either one or a combination of the following: 1) containing artificial flavour mimicking test food 2) containing artificial colour mimicking test food 3) containing same energy content as test food 4) containing same food matrix as test food
- Main Outcome
- This review will measure the effect size (Cohen's d) between treatment versus control group of the following outcomes: 1) Blood glucose 2) Systolic blood pressure (SBP) 3) Diastolic blood pressure (DBP) 4) LDL-c levels 5) HDL-c levels Measures of effect An effect size of 0.2, 0.5 and 0.8 are considered as small, medium and large, respectively.
- Outcome Measure
- Additional Outcome
- A change from baseline (before) and after treatment. Measures of effect The change in item 25 will be measured as percentage (%) change.
- Study Method
- Intervention, Meta-analysis, Systematic review
- Keyword
- Cacao; Chocolate; Food; Humans; Metabolic Syndrome; Physiological Phenomena
- Contact
- Sharvintha Salaish Kumar [email protected]
- Organisational Affiliation
- Universiti Sultan Zainal Abidin (UniSZA), Malaysia www.unisza.edu.my
- Funding Source
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- Malaysia
- Review Stage
- Review Ongoing
- First Submission Date
- 2023-01-04
- Registration Date
- 2023-01-15
- Anticipated Start Date
- 2022-12-01
- Anticipated Completion Date
- 2023-06-30
- Title Cn
- 可可对代谢综合征结局的影响：系统评价与Meta分析
- Title En
- Effect of Cocoa on Metabolic Syndrome Outcomes: A Systematic Review and Meta-Analysis
- Bilingual Status
- complete