Meta AnalysisID 4060
基因多态性对苯暴露工人影响的系统评价
CRD42020210759
Do genetic polymorphisms increase the risk of developing adverse health-related outcomes and changes in urinary biomarkers on benzene-exposed workers?
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Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 4060
- Evidence Id
- 12618
- Core Evidence Id
- 12618
- Source Meta Analysis Id
- 4019
- Herb2 Meta Analysis Id
- HBMA004019
- Crd Id
- CRD42020210759
- Title
- The effects of genetic polymorphisms on benzene exposed workers: a systematic review
- Review Question
- Do genetic polymorphisms increase the risk of developing adverse health-related outcomes and changes in urinary biomarkers on benzene-exposed workers?
- Study Type Included
- The accepted types of research will be observational studies such as cross-sectional, case-control, retrospective and prospective studies
- Condition Being Studied
- Occupational medicine. Occupational benzene exposure. Adverse health-related outcomes and changes in urinary biomarkers related to benzene exposure.
- Participant
- Human subjects older than 18, whose main source of benzene exposure is occupational (not environmental).
- Animal
- Human Disease Modelled
- Intervention
- The presence of genetic polymorphisms in workers chronically exposed to benzene.
- Comparator Control
- Workers chronically exposed to benzene without those genetic polymorphisms.
- Main Outcome
- The increase on the risk of developing adverse health-related outcomes and changes in urinary biomarkers Measures of effect Measured by odds ratios
- Outcome Measure
- Additional Outcome
- Changes in the excretion of urinary biomarkers Measures of effect Measured by the difference in the concentration of benzene related biomarkers in the urine.
- Study Method
- Systematic review
- Keyword
- Benzene; Humans; Occupational Exposure; Polymorphism, Genetic; X-ray Repair Cross Complementing Protein 1
- Contact
- Veronica Ramirez [email protected]
- Organisational Affiliation
- Universidad de Antioquia
- Funding Source
- This study was supported by a grant from the Ministerio de Ciencia, Tecnología e Innovación Grant number(s) <span style=font-size: 14px>State the funder, grant or award number and the date of award</span> (Contract RC.847-2019).
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- Colombia
- Review Stage
- Review Ongoing
- First Submission Date
- 2020-09-22
- Registration Date
- 2020-10-23
- Anticipated Start Date
- 2020-04-16
- Anticipated Completion Date
- 2020-11-01
- Title Cn
- 基因多态性对苯暴露工人影响的系统评价
- Title En
- The effects of genetic polymorphisms on benzene exposed workers: a systematic review
- Bilingual Status
- complete