Meta AnalysisID 4032
膳食苯并(a)芘及杂环胺与癌症风险：队列研究的系统评价与Meta分析
CRD42021283600
1- Doese dietary Benzo(a)Pyrene intake increase the risk of different cancers? 2- Doese dietary Heterocyclic Aromatic Amines intake increase the risk of different cancers? 3- Which benzo(a)pyrene or Heterocyclic Aromatic
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Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 4032
- Evidence Id
- 12590
- Core Evidence Id
- 12590
- Source Meta Analysis Id
- 3990
- Herb2 Meta Analysis Id
- HBMA003990
- Crd Id
- CRD42021283600
- Title
- Dietary bnzo(a)pyrene and heterocyclic aromatic amines and the risk of cancer: a systematic review and meta-analysis of cohort studies
- Review Question
- 1- Doese dietary Benzo(a)Pyrene intake increase the risk of different cancers? 2- Doese dietary Heterocyclic Aromatic Amines intake increase the risk of different cancers? 3- Which benzo(a)pyrene or Heterocyclic Aromatic Amines intake is more effective in increasing the risk of cancer?
- Study Type Included
- Cohort studies
- Condition Being Studied
- Cancer is a chronic disease with abnormal cell proliferation. Incidence of cancer has close relationship with dietary components such as polycyclic aromatic hydrocarbone and heterocyclic aromatic amines. different types of cancer such as prostate cancer, breast cancer, colorectal cancer, pancreatic cancer, and other were studied in this topic.
- Participant
- Inclusion criteria: 1. 80 percent follow-up is being used as the minimum acceptable 2. Studies that contain hazard ratio(HR) or relative risk(RR) of Benzo(a)pyrene and HCA with 95% confidence intervals in cancer 3. Prospective studies Exclusion criteria: 1. less than 80 percent follow-up 2. Prospectiv studies which doesn’t have ER or RR of population
- Animal
- Human Disease Modelled
- Intervention
- Benzo(a)pyrene and heterocyclic amins are a bunches of Food contaminant. They are produced in the food through the process of cooking such as Grilling, smoking, frying and drying. These contaminants can affect genes, enzymes, apoptosis and other cancer-related processes, thus playing a role in causing cancer.
- Comparator Control
- A group of healthy adults who were exposed to the Bap and HCA but they don’t given cancer.
- Main Outcome
- Increase cancer risk in adults that intake more Bap and HCA in the end of follow up Measures of effect 1) Odd ratios 2) Hazard ratios
- Outcome Measure
- Additional Outcome
- Increase cancer risk in specific ethnicity and specific cancer
- Study Method
- Prospective meta-analysis (PMA), Systematic review
- Keyword
- Amines; Cohort Studies; Heterocyclic Compounds; Humans; Neoplasms; Pyrenes
- Contact
- Dr Saeed Pirouzpanah [email protected]
- Organisational Affiliation
- Department of Biochemistry and Dietetics, Faculty of Nutrition and Food Sciences, Tabriz University of Medical Science, Tabriz, Iran
- Funding Source
- nothing
- Other Selection Criteria
- Final Publication
- Same Topic Review
- nothing
- Published Protocol
- Review Type
- Language
- English
- Country
- Iran
- Review Stage
- Review Ongoing
- First Submission Date
- 2021-10-06
- Registration Date
- 2021-11-06
- Anticipated Start Date
- 2021-10-01
- Anticipated Completion Date
- 2021-11-20
- Title Cn
- 膳食苯并(a)芘及杂环胺与癌症风险：队列研究的系统评价与Meta分析
- Title En
- Dietary bnzo(a)pyrene and heterocyclic aromatic amines and the risk of cancer: a systematic review and meta-analysis of cohort studies
- Bilingual Status
- complete