Meta AnalysisID 4029
外用中效糖皮质激素对比PUVA（补骨脂素加长波紫外线照射）治疗成人汗疱疹
CRD42019123659
What is the effectiveness and safety of topical treatment with medium-potency corticosteroids and PUVA photodynamic therapy (therapy with psoralen plus ultraviolet A radiation) for the treatment of dyshidrosis in adult p
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Record Fields
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- Meta Analysis Id
- 4029
- Evidence Id
- 12587
- Core Evidence Id
- 12587
- Source Meta Analysis Id
- 3987
- Herb2 Meta Analysis Id
- HBMA003987
- Crd Id
- CRD42019123659
- Title
- Topical medium potency corticosteroids compared to PUVA (psoralen plus ultraviolet A radiation) for the treatment of pompholyx in adult patients
- Review Question
- What is the effectiveness and safety of topical treatment with medium-potency corticosteroids and PUVA photodynamic therapy (therapy with psoralen plus ultraviolet A radiation) for the treatment of dyshidrosis in adult patients aged 18 to 59 years?
- Study Type Included
- Randomized and non randomized clinical trials. Exclusion: epidemiological studies, review articles and articles published in a language other than English or Spanish
- Condition Being Studied
- Dyshidrosis (pompholyx) is a chronic, recurrent inflammatory disease, a condition characterized by vesicles or blisters without underlying erythema affecting the lateral faces of fingers, palms and soles. It is often associated with hyperhidrosis. In histology, fluid is trapped under the stratum corneum in the form of taut white blisters resembling grains of rice; Spongiosis, hyperkeratosis, hypergranulosis, intraepidermal spongiotic vesicles are observed. The acrosiringio of the sweat glands is not altered. Patients usually have itching and burning.
- Participant
- Inclusion: Patients older than 18 years, <59 years with clinical and/or histological diagnosis of dyshidrosis/pompholyx.
- Animal
- Human Disease Modelled
- Intervention
- Treatment with topical medium potency corticosteroids and treatment with psoralen plus ultraviolet A radiation (PUVA).
- Comparator Control
- Direct and indirect comparisons between treatments with medium-potency topical corticosteroids and PUVA.
- Main Outcome
- Clinical improvement assessed by a dermatologist using Dyshidrotic Eczema Area and Severity Index (DASI). Measures of effect None
- Outcome Measure
- Additional Outcome
- Recurrence after treatment, treatment adverse effects, patient satisfaction, and quality of life. Measures of effect None
- Study Method
- Systematic review
- Keyword
- Adult; Dermatologic Agents; Eczema, Dyshidrotic; Ficusin; Glucocorticoids; Humans; PUVA Therapy; Ultraviolet Rays
- Contact
- Laura Haydee Camacho Rosas [email protected]
- Organisational Affiliation
- Dermatological Center Dr Ladislao de la Pascua, Mexico City, Mexico Dr. Vértiz #464, Colonia Buenos aires, Delegación Cuauhtémoc. Ciudad de México, México.
- Funding Source
- None.
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- Mexico
- Review Stage
- Review Ongoing
- First Submission Date
- 2019-01-30
- Registration Date
- 2019-06-14
- Anticipated Start Date
- 2019-01-29
- Anticipated Completion Date
- 2020-01-29
- Title Cn
- 外用中效糖皮质激素对比PUVA（补骨脂素加长波紫外线照射）治疗成人汗疱疹
- Title En
- Topical medium potency corticosteroids compared to PUVA (psoralen plus ultraviolet A radiation) for the treatment of pompholyx in adult patients
- Bilingual Status
- complete