Meta AnalysisID 4006

含动物双歧杆菌乳亚种CNCM I-2494/DN-173010和乳酸菌的发酵乳制品对一般人群胃肠道不适影响的系统评价与Meta分析

CRD42015016660

Is a fermented milk product that includes Bifidobacteria animalis ssp lactis CNCM I-2494/DN-173010 and lactic acid bacteria effective in reducing gastrointestinal discomfort in the general adult population.

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Record Fields

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Meta Analysis Id
4006
Evidence Id
12564
Core Evidence Id
12564
Source Meta Analysis Id
3962
Herb2 Meta Analysis Id
HBMA003962
Crd Id
CRD42015016660
Title
Systematic review and meta-analysis of the effects of a fermented milk product that includes Bifidobacteria animalis ssp lactis CNCM I-2494/DN-173010 and lactic acid bacteria on gastrointestinal discomfort in the general population
Review Question
Is a fermented milk product that includes Bifidobacteria animalis ssp lactis CNCM I-2494/DN-173010 and lactic acid bacteria effective in reducing gastrointestinal discomfort in the general adult population.
Study Type Included
Inclusion criteria: double-blind prospective randomised controlled trials; single blind studies will be summarised in the discussion only; Exclusion criteria: unblinded trials
Condition Being Studied
Participant
Animal
Human Disease Modelled
Intervention
Inclusion criteria: Fermented milk product that includes Bifidobacteria animalis ssp lactis CNCM I-2494/DN-173010 and lactic acid bacteria (any dose) consumed for at least four weeks. Exclusion criteria: A fermented milk product that includes Bifidobacteria animalis ssp lactis CNCM I-2494/DN-173010 and lactic acid bacteria combined with other functional ingredients such as prebiotics or vitamins.
Comparator Control
Eligible comparators: A control product which may include other live bacteria, such as yogurt cultures. A control product can be: • non-fermented dairy products without probiotics with same taste, colour appearance (to allow double-blinding); • the heat-treated active product (i.e. the bacteria are not alive in the control product and the probiotics (living Bifidobacteria bacteria) are compared to dead bacteria in the same dairy matrix); • another fermented milk product without “active” probiotics (e.g. a standard yoghurt without the Bifidobacteria). Ineligible criteria: • a fermented milk product that includes Bifidobacteria animalis ssp lactis CNCM I-2494/DN-173010 and lactic acid bacteria combined with additional ingredients, such as prebiotics, which are different to additional ingredients included in the intervention. • Standard yoghurts containing Bifidobacteria; • Other prebiotics.
Main Outcome
Outcome Measure
Additional Outcome
Study Method
Keyword
Bifidobacterium; Cultured Milk Products; Gastrointestinal Diseases; Humans; Lactic Acid; Probiotics
Contact
Organisational Affiliation
Funding Source
Other Selection Criteria
Final Publication
Same Topic Review
Published Protocol
Review Type
Language
English
Country
England
Review Stage
First Submission Date
Registration Date
2015-02-10
Anticipated Start Date
Anticipated Completion Date
Title Cn
含动物双歧杆菌乳亚种CNCM I-2494/DN-173010和乳酸菌的发酵乳制品对一般人群胃肠道不适影响的系统评价与Meta分析
Title En
Systematic review and meta-analysis of the effects of a fermented milk product that includes Bifidobacteria animalis ssp lactis CNCM I-2494/DN-173010 and lactic acid bacteria on gastrointestinal discomfort in the general population
Bilingual Status
complete