Meta AnalysisID 3926

新型钾结合剂在心力衰竭患者中的安全性与有效性:随机对照试验的Meta分析

CRD42022353010

P: patients with heart failure with a previous history or at risk of hyperkalemia. I: New potassium binders (Patiromer and Sodium zirconium cyclosilicate) C: Placebo O: Medical therapy optimization, incidence of hyper- a

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Record Fields

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Meta Analysis Id
3926
Evidence Id
12484
Core Evidence Id
12484
Source Meta Analysis Id
3885
Herb2 Meta Analysis Id
HBMA003885
Crd Id
CRD42022353010
Title
Safety and Efficacy of New Potassium Binders in Patients with Heart Failure: A Meta-analysis of Randomized Controlled Trials
Review Question
P: patients with heart failure with a previous history or at risk of hyperkalemia. I: New potassium binders (Patiromer and Sodium zirconium cyclosilicate) C: Placebo O: Medical therapy optimization, incidence of hyper- and hypokalemia, all-cause mortality
Study Type Included
Only randomized controlled trials
Condition Being Studied
Heart failure
Participant
Patients with heart failure with a previous medical history of hyperkalemia or at risk of its development
Animal
Human Disease Modelled
Intervention
New potassium binders (patiromer and sodium zirconium cyclosilicate)
Comparator Control
Placebo
Main Outcome
Medical therapy optimization Measures of effect Odds-ratio
Outcome Measure
Additional Outcome
Incidence of hyper- or hypokalemia Mortality Adverse events (diarrhea, constipation, nausea, hypomagnesemia) Measures of effect Odds-ratio
Study Method
Intervention, Meta-analysis, Systematic review
Keyword
Heart Failure; Humans; Potassium; Randomized Controlled Trials as Topic
Contact
PEDRO CARVALHO [email protected]
Organisational Affiliation
FEDERAL UNIVERSITY OF MINAS GERAIS
Funding Source
This work has no funding.
Other Selection Criteria
Final Publication
Same Topic Review
Published Protocol
Review Type
Language
English
Country
Brazil
Review Stage
Review Ongoing
First Submission Date
2022-08-11
Registration Date
2022-08-22
Anticipated Start Date
2022-08-09
Anticipated Completion Date
2022-10-01
Title Cn
新型钾结合剂在心力衰竭患者中的安全性与有效性:随机对照试验的Meta分析
Title En
Safety and Efficacy of New Potassium Binders in Patients with Heart Failure: A Meta-analysis of Randomized Controlled Trials
Bilingual Status
complete