Meta AnalysisID 3880

静脉注射利多卡因治疗成年住院患者外周氯化钾输注相关疼痛的有效性:一项系统评价方案

CRD42014014450

The objective of this review is to identify the effectiveness of intravenous Lidocaine used to treat pain related to peripheral potassium chloride infusion in adult patients in a hospital setting.

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Record Fields

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Meta Analysis Id
3880
Evidence Id
12438
Core Evidence Id
12438
Source Meta Analysis Id
3837
Herb2 Meta Analysis Id
HBMA003837
Crd Id
CRD42014014450
Title
The effectiveness of intravenous Lidocaine used to treat pain related to peripheral potassium chloride infusion in adult hospitalized patients: a systematic review protocol
Review Question
The objective of this review is to identify the effectiveness of intravenous Lidocaine used to treat pain related to peripheral potassium chloride infusion in adult patients in a hospital setting.
Study Type Included
This review will consider any experimental study design including randomized controlled trials, non-randomized controlled trials, quasi-experimental studies and before and after studies for inclusion.
Condition Being Studied
Hypokalemia disrupts normal homeostasis and occurs in among 20% of hospitalized patients, with the most common cause being the depletion of potassium ions (K+) from gastrointestinal or urinary losses. Intravenous potassium chloride infusion is often used to treat hypokalemia, and is proven to be a relatively safe treatment of hypokalemia in about 20% of the hospitalized patients. However this infusion can cause severe acute pain via a peripherally inserted catheter at the infusion site. The etiology of pain associated with peripheral infusion of potassium chloride is unknown. To increase patients’ tolerance to peripheral potassium chloride infusion the intravenous use of Lidocaine is recommended. The scope of this systematic review will focus on identifying if intravenous Lidocaine is effective in alleviating pain at the infusion site while infusing intravenous potassium chloride via a peripheral inserted catheter.
Participant
This review will consider studies that include all adult patients treated in the hospital setting who are the recipients of peripheral potassium chloride infusion. Adult patients are defined as all participants aged older than 18 years of age.
Animal
Human Disease Modelled
Intervention
This review will consider studies that evaluate: •
Comparator Control
Main Outcome
Outcome Measure
Additional Outcome
Study Method
Keyword
Administration, Intravenous; Humans; Inpatients; Lidocaine; Pain; Potassium Chloride
Contact
Organisational Affiliation
Funding Source
Other Selection Criteria
Final Publication
Same Topic Review
Published Protocol
Review Type
Language
English
Country
Review Stage
First Submission Date
Registration Date
Anticipated Start Date
Anticipated Completion Date
Title Cn
静脉注射利多卡因治疗成年住院患者外周氯化钾输注相关疼痛的有效性:一项系统评价方案
Title En
The effectiveness of intravenous Lidocaine used to treat pain related to peripheral potassium chloride infusion in adult hospitalized patients: a systematic review protocol
Bilingual Status
complete