Meta AnalysisID 3863
邻苯二甲酸二(2-乙基己基)酯(DEHP)暴露与血清甲状腺激素水平的关联：系统评价与Meta分析
CRD42022337510
The aim was to use systematic review and meta-analysis to determine the association of diethylhexyl phthalate exposure with thyroid function
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Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 3863
- Evidence Id
- 12421
- Core Evidence Id
- 12421
- Source Meta Analysis Id
- 3818
- Herb2 Meta Analysis Id
- HBMA003818
- Crd Id
- CRD42022337510
- Title
- Association of diethylhexyl phthalate (DEHP) exposure with serum thyroid hormone levels: a systematic review and meta-analysis
- Review Question
- The aim was to use systematic review and meta-analysis to determine the association of diethylhexyl phthalate exposure with thyroid function
- Study Type Included
- Cohort study, case-controlled study or cross‑sectional study.
- Condition Being Studied
- As one of the environmental endocrine disruptors, phthalates have been proved to have anti-estrogen, anti-androgen, anti-progesterone and anti-thyroid function, which have negative effects on human health. At present, there have been several population epidemiological studies on the effects of PAEs exposure with thyroid function. However, the types of related metabolites in each study are different, the outcome indicators are not consistent, and the conclusions are controversial. Therefore, we conducted a meta-analysis to clarify the relationship between diethylhexyl phthalate exposure and thyroid function, and to provide scientific basis for exploring the etiology of thyroid diseases.
- Participant
- general population
- Animal
- Human Disease Modelled
- Intervention
- diethylhexyl phthalate exposure
- Comparator Control
- No comparators are available in this study.
- Main Outcome
- thyroid hormones Measures of effect TSH, T3, fT3, T4, fT4
- Outcome Measure
- Additional Outcome
- No
- Study Method
- Meta-analysis, Systematic review
- Keyword
- Diethylhexyl Phthalate; Female; Humans; Phthalic Acids; Prenatal Exposure Delayed Effects; Thyroid Hormones
- Contact
- huan sun [email protected]
- Organisational Affiliation
- West China Hospital of Sichuan University
- Funding Source
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- China
- Review Stage
- Review Ongoing
- First Submission Date
- 2022-06-04
- Registration Date
- 2022-06-15
- Anticipated Start Date
- 2022-05-14
- Anticipated Completion Date
- 2022-11-14
- Title Cn
- 邻苯二甲酸二(2-乙基己基)酯(DEHP)暴露与血清甲状腺激素水平的关联：系统评价与Meta分析
- Title En
- Association of diethylhexyl phthalate (DEHP) exposure with serum thyroid hormone levels: a systematic review and meta-analysis
- Bilingual Status
- complete