Meta AnalysisID 3851

化妆品中对羟基苯甲酸酯类防腐剂的毒性与安全性:一项系统评价

CRD42019135888

How toxic are the parabens used as preservatives in cosmetics, and how safe are they?

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Record Fields

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Meta Analysis Id
3851
Evidence Id
12409
Core Evidence Id
12409
Source Meta Analysis Id
3805
Herb2 Meta Analysis Id
HBMA003805
Crd Id
CRD42019135888
Title
The toxicity and safety of parabens as preservatives in cosmetics: a systematic review
Review Question
How toxic are the parabens used as preservatives in cosmetics, and how safe are they?
Study Type Included
Inclusion: randomized clinical trials, cohort studies (observational), case reports, case control and case series; studies in Roman alphabet languages that evaluate the toxicity and safety of the use of parabens in cosmetics. Exclusion: studies evaluating the general characteristics of cosmetics containing parabens; animal studies; review studies; and studies with unavailable abstracts.
Condition Being Studied
The safety and toxicity of parabens in cosmetics.
Participant
Inclusion: studies in Roman characters that evaluate the toxicity and safety of the use of parabens in cosmetics. Exclusion: studies evaluating the general characteristics of cosmetics containing parabens; animal studies; review study; studies with the abstract unavailable.
Animal
Human Disease Modelled
Intervention
Individuals using cosmetics containing any kind of paraben in any dose or contact test including paraben.
Comparator Control
Any other preservative or placebo or no control group.
Main Outcome
To evaluate the toxicity and safety of the use of parabens in cosmetics. Measures of effect Not applicable.
Outcome Measure
Additional Outcome
None. Measures of effect Not applicable.
Study Method
Epidemiologic, Systematic review
Keyword
Consumer Product Safety; Cosmetics; Humans; Parabens; Preservatives, Pharmaceutical; Public Health; Risk; Risk Assessment; Safety; Toxic Actions
Contact
Aline Carolina Favoretto Cordeiro [email protected]
Organisational Affiliation
Federal University of Paraná - UFPR Av. Prefeitura Lothario Meissner 632, Curitiba, PR
Funding Source
PPGCF - Post Graduation Program in Pharmaceutical Sciences Scholarship by Coordination of Improvement of Higher Level Personnel (CAPES)
Other Selection Criteria
Final Publication
Same Topic Review
Published Protocol
Review Type
Language
English, Portuguese-Brazil
Country
Brazil
Review Stage
Review Ongoing
First Submission Date
2019-05-17
Registration Date
2019-09-17
Anticipated Start Date
2019-04-17
Anticipated Completion Date
2020-02-01
Title Cn
化妆品中对羟基苯甲酸酯类防腐剂的毒性与安全性:一项系统评价
Title En
The toxicity and safety of parabens as preservatives in cosmetics: a systematic review
Bilingual Status
complete