Meta AnalysisID 3730

橄榄苦苷摄入对成年人群心血管疾病的抗氧化效应:一项系统评价

CRD42021273708

What is the antioxidant effect of oleuropein via oral consumption in cardiovascular diseases?

Back to Browse

Relationship Network

Interactive first-hop connections across herbs, ingredients, formulas, targets, diseases, symptoms, syndromes, evidence, and monographs.

Click a node to open it in a new tab
Ingredient: 1Meta-analysis: 1Links: 1
Arranging relationship network...

Record Fields

Scalar fields from the final meta_analysis record.

Meta Analysis Id
3730
Evidence Id
12288
Core Evidence Id
12288
Source Meta Analysis Id
3691
Herb2 Meta Analysis Id
HBMA003691
Crd Id
CRD42021273708
Title
The antioxidant effect of oleuropein consumption on cardiovascular disease in the adult population: a systematic review.
Review Question
What is the antioxidant effect of oleuropein via oral consumption in cardiovascular diseases?
Study Type Included
Inclusion criteria: Studies that evaluate the consumption of oleuropein orally. Human studies. Adults (aged 18 - 65 years) with previously cardiovascular disease or cardio-metabolic risks (Coronary artery disease, High pressure, Cardiac insufficiency, Cardiac arrhythmia, Peripheral arterial disease, Heart Diseases, Brain stroke) Clinical trials and randomized clinical trials. Exclusion criteria: experimental studies in vitro, experimental studies with animals, cross-sectional, case-control, cohort studies, review articles and metaanalyzes. Pregnant Women and Infants. Studies with children or adolescents. Studies with the Elderly. Observational studies, Review studies, meta-analyzes. Animal studies. In vitro studies.
Condition Being Studied
Knowing that cardiovascular diseases are the major cause of death nowadays, it is of collective importance to study such comorbidities in order to assist in the treatment and also to possibly reduce drug consumption in this population. In view of the cardiometabolic effects of such comorbidities and the high level of stress caused, our review intends to evaluate the potential antioxidant effect of oleuropein - a compound present in olive oil, as well as in all its parts - in cardiovascular diseases.
Participant
Adults with previously cardiovascular disease aged 18-65 years.
Animal
Human Disease Modelled
Intervention
Oral consumption of oleuropein.
Comparator Control
Placebo.
Main Outcome
Comorbidities such as cardio-metabolic risks or cardiovascular diseases (Coronary artery disease, High pressure, Cardiac insufficiency, Cardiac arrhythmia, Peripheral arterial disease, Heart Diseases, Brain stroke). Measures of effect Safety and effectiveness.
Outcome Measure
Additional Outcome
None Measures of effect None
Study Method
Systematic review
Keyword
Adult; Antioxidants; Cardiovascular Diseases; Humans; Iridoid Glucosides; Iridoids; oleuropein
Contact
Kathleen Kruger Peres [email protected]
Organisational Affiliation
UFCSPA
Funding Source
None Grant number(s) <span style=font-size: 14px>State the funder, grant or award number and the date of award</span> None
Other Selection Criteria
Final Publication
Same Topic Review
Published Protocol
Review Type
Language
English
Country
Brazil
Review Stage
Review Ongoing
First Submission Date
2021-08-15
Registration Date
2021-09-15
Anticipated Start Date
2021-08-15
Anticipated Completion Date
2022-04-15
Title Cn
橄榄苦苷摄入对成年人群心血管疾病的抗氧化效应:一项系统评价
Title En
The antioxidant effect of oleuropein consumption on cardiovascular disease in the adult population: a systematic review.
Bilingual Status
complete