Meta AnalysisID 3711
去氧肾上腺素对比去甲肾上腺素在脓毒症患者中的应用：一项Meta分析
CRD42022372008
Will the use of phenylephrine improve mortality and also have beneficial outcomes in septic shock management compared to norepinephrine use
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Record Fields
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- Meta Analysis Id
- 3711
- Evidence Id
- 12269
- Core Evidence Id
- 12269
- Source Meta Analysis Id
- 3669
- Herb2 Meta Analysis Id
- HBMA003669
- Crd Id
- CRD42022372008
- Title
- Use of Phenylephrine Compared to Norepinephrine In Patients With Sepsis; A Meta-analysis
- Review Question
- Will the use of phenylephrine improve mortality and also have beneficial outcomes in septic shock management compared to norepinephrine use
- Study Type Included
- RCT, retrospective and prospective cohort studies,
- Condition Being Studied
- Sepsis, septic shock
- Participant
- Patients who have a diagnosis of sepsis and require vasopressor use, specifically norepinephrine or phenylephrine
- Animal
- Human Disease Modelled
- Intervention
- A comprehensive literature search of PubMed and EMBASE will be conducted and all relevant studies that compared phenylephrine to norepinephrine in sepsis patients will be included. The eligibility criteria are follows: study was published in a peer-reviewed journal; the design was either retrospective/prospective cohort study or randomized control study that compared phenylephrine use and norepinephrine use in sepsis patients Exclusion criteria are as follows: study was not published in a peer reviewed journal
- Comparator Control
- The patient who are using norepinephrine will be the control for this study which looks into the phenylephrine population.
- Main Outcome
- Our primary outcome is in-hospital mortality. 30-day mortality will be alternatively used if data for in-hospital mortality is not available.
- Outcome Measure
- Additional Outcome
- Our secondary outcomes are change in heart rate, hospital and intensive care unit length of stay.
- Study Method
- Meta-analysis, Systematic review
- Keyword
- Humans
- Contact
- Yoshiko Ishisaka [email protected]
- Organisational Affiliation
- Mount Sinai Beth Israel
- Funding Source
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- Japan, United States of America
- Review Stage
- Review Ongoing
- First Submission Date
- 2022-11-01
- Registration Date
- 2022-11-11
- Anticipated Start Date
- 2022-11-09
- Anticipated Completion Date
- 2023-01-31
- Title Cn
- 去氧肾上腺素对比去甲肾上腺素在脓毒症患者中的应用：一项Meta分析
- Title En
- Use of Phenylephrine Compared to Norepinephrine In Patients With Sepsis; A Meta-analysis
- Bilingual Status
- complete