Meta AnalysisID 3709

预防性静脉注射去甲肾上腺素预防择期剖宫产脊麻期间低血压的剂量-反应Meta分析

CRD42022349934

To determine the optimal dose of prophylactic IV norepinephrine for preventing maternal hypotension during spinal anesthesia for cesarean section.

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Record Fields

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Meta Analysis Id
3709
Evidence Id
12267
Core Evidence Id
12267
Source Meta Analysis Id
3667
Herb2 Meta Analysis Id
HBMA003667
Crd Id
CRD42022349934
Title
A Dose-Response Meta-Analysis of Prophylactic Intravenous Norepinephrine for the Prevention of Hypotension During Spinal Anesthesia for Elective Cesarean Section
Review Question
To determine the optimal dose of prophylactic IV norepinephrine for preventing maternal hypotension during spinal anesthesia for cesarean section.
Study Type Included
Randomized controlled trial (RCT).
Condition Being Studied
Prophylactic intravenous norepinephrine and hypotension during spinal anesthesia for elective cesarean section.
Participant
Women undergoing spinal anesthesia for elective cesarean section.
Animal
Human Disease Modelled
Intervention
More than one different bolus dose of IV norepinephrine.
Comparator Control
Reference group (0 mg).
Main Outcome
Maternal hypotension. Measures of effect Relative risks.
Outcome Measure
Additional Outcome
Maternal hypertension, maternal nausea or vomiting, umbilical cord arterial blood gases, fetal acidosis, and Apgar scores. Measures of effect Relative risks.
Study Method
Intervention, Meta-analysis, Systematic review
Keyword
Anesthesia, Obstetrical; Anesthesia, Spinal; Cesarean Section; Female; Humans; Hypotension; Norepinephrine; Pregnancy
Contact
Yuan Li [email protected]
Organisational Affiliation
Department of Anesthesiology,West China Second Hospital of Sichuan University,Key Laboratory of Birth Defects and Related Diseases of Women and Children,Sichuan University,Ministry of Education,Chengdu, China https://www.motherchildren.com
Funding Source
NO
Other Selection Criteria
Final Publication
Same Topic Review
Published Protocol
Review Type
Language
English
Country
China
Review Stage
Review Ongoing
First Submission Date
2022-07-29
Registration Date
2022-08-09
Anticipated Start Date
2022-07-25
Anticipated Completion Date
2022-12-31
Title Cn
预防性静脉注射去甲肾上腺素预防择期剖宫产脊麻期间低血压的剂量-反应Meta分析
Title En
A Dose-Response Meta-Analysis of Prophylactic Intravenous Norepinephrine for the Prevention of Hypotension During Spinal Anesthesia for Elective Cesarean Section
Bilingual Status
complete