Meta AnalysisID 3684

儿童茶碱的最佳治疗范围是什么?

CRD42015026600

What is the optimum therapeutic range for theophyllines in children?

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Record Fields

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Meta Analysis Id
3684
Evidence Id
12242
Core Evidence Id
12242
Source Meta Analysis Id
3643
Herb2 Meta Analysis Id
HBMA003643
Crd Id
CRD42015026600
Title
What is the optimum therapeutic range for theophyllines in children?
Review Question
What is the optimum therapeutic range for theophyllines in children?
Study Type Included
RCTs, crossover trials, Cohort studies, cross sectional studies, case control studies.Review papers will be excluded
Condition Being Studied
Asthma in children
Participant
Children (18 Years or less) with asthma requiring treatment with theophyllines (either oral or IV) for either acute or chronic asthma
Animal
Human Disease Modelled
Intervention
Intervention: A dose of theophylline (either oral theophylline or IV aminophylline)which achieves a certain therapeutic range which results in a improvement of symptoms
Comparator Control
A dose of theophylline (either oral theophylline or IV aminophylline) which achieves a therapeutic range which fails to result in an improvement of symptoms
Main Outcome
Resolution of symptoms Date till ready for discharge Mortality Major adverse effects (arrhythmias, seizures)
Outcome Measure
Additional Outcome
Spirometry results (PEFR, FEV1) Number of exacerbations Quality of Life Days off school
Study Method
Keyword
Asthma; Child; Humans; Theophylline
Contact
Mr Cooney [email protected]
Organisational Affiliation
University of Liverpool liv.ac.uk
Funding Source
NHS bursary for MPhil
Other Selection Criteria
Final Publication
Same Topic Review
Published Protocol
Review Type
Language
English
Country
England
Review Stage
Review Ongoing
First Submission Date
Registration Date
2015-09-25
Anticipated Start Date
2015-09-05
Anticipated Completion Date
2015-12-04
Title Cn
儿童茶碱的最佳治疗范围是什么?
Title En
What is the optimum therapeutic range for theophyllines in children?
Bilingual Status
complete