Meta AnalysisID 3683
氨茶碱治疗硬脊膜穿刺后头痛的安全性和有效性：一项随机对照试验的Meta分析
CRD42022296438
The primary objective of the current systematic review and meta-analysis is to investigate the Safety and effectiveness of aminophylline for treatment of post-dural puncture headache.
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Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 3683
- Evidence Id
- 12241
- Core Evidence Id
- 12241
- Source Meta Analysis Id
- 3642
- Herb2 Meta Analysis Id
- HBMA003642
- Crd Id
- CRD42022296438
- Title
- The Safety and effectiveness of Aminophylline for treatment of postdural puncture headache: A meta-analysis of randomised controlled trials
- Review Question
- The primary objective of the current systematic review and meta-analysis is to investigate the Safety and effectiveness of aminophylline for treatment of post-dural puncture headache.
- Study Type Included
- Only randomized controlled studies are included for analysis. Letter, case series, review, before-after studies are excluded.
- Condition Being Studied
- Postdural puncture headache (PDPH) is a major complication of neuraxial anesthesia. Epidural blood patch remains the standardized treatment. However, an epidural blood patch may bring some complications such as infection. And some studies had reported that the use of aminophylline may prevent or treat the post-dural puncture headache. However, the efficacy of aminophylline remains to be clarified.
- Participant
- All participants (male, female, or both) undergoing lumbar puncture will be eligible to be analyzed in this systematic review and meta-analysis.
- Animal
- Human Disease Modelled
- Intervention
- Aminophylline is given as intervention. Different dosages of aminophylline are included. Only randomized controlled trials are included.
- Comparator Control
- Placebo or other analgesia drugs are used as comparators
- Main Outcome
- The risk of post-dural puncture headahce is the primary outcome.
- Outcome Measure
- Additional Outcome
- Severity of pain or pain relief is used as the secondary outcome.
- Study Method
- Intervention, Meta-analysis, Systematic review
- Keyword
- Aminophylline; Humans; Needles; Post-Dural Puncture Headache; Spinal Puncture
- Contact
- Zhen-zhao Huang [email protected]
- Organisational Affiliation
- Hangzhou Women's Hospital http://www.hzwmhp.com/
- Funding Source
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- China
- Review Stage
- Review Ongoing
- First Submission Date
- 2021-12-05
- Registration Date
- 2022-01-05
- Anticipated Start Date
- 2021-11-25
- Anticipated Completion Date
- 2022-11-25
- Title Cn
- 氨茶碱治疗硬脊膜穿刺后头痛的安全性和有效性：一项随机对照试验的Meta分析
- Title En
- The Safety and effectiveness of Aminophylline for treatment of postdural puncture headache: A meta-analysis of randomised controlled trials
- Bilingual Status
- complete