Meta AnalysisID 3682
氨茶碱用于预防或治疗硬脊膜穿刺后头痛：一项Meta分析
CRD42020207713
To explore whether the use of aminophylline can prevent or treat the postdural puncture headache in adult patients receiving regional anesthesia
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Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 3682
- Evidence Id
- 12240
- Core Evidence Id
- 12240
- Source Meta Analysis Id
- 3641
- Herb2 Meta Analysis Id
- HBMA003641
- Crd Id
- CRD42020207713
- Title
- The use of aminophylline to prevent or treat post-dural puncture headache: a meta-analysis
- Review Question
- To explore whether the use of aminophylline can prevent or treat the postdural puncture headache in adult patients receiving regional anesthesia
- Study Type Included
- Only randomized controlled studies are included for analysis. Letter, case series, review, before-after studies are excluded.
- Condition Being Studied
- Post-dural puncture headache may occur following regional anesthesia. Epidural blood patch remains the standardized treatment. Some studies had reported that the use of aminophylline may prevent or treat the post-dural puncture headache. However, the efficacy of aminophylline remains to be clarified.
- Participant
- Adult patients who are scheduled to receive regional anesthesia or adult patients who are diagnosed with post-dural puncture headache Inclusion criteria: adult patients aged more than 18 years, no allery to aminophylline, no other neurological disease Exclusion criteria: pediatric population, headache not associated with dural puncture, no history of regional anesthesia
- Animal
- Human Disease Modelled
- Intervention
- Aminophylline is given as intervention. Different dosages of aminophylline are included. Only randomized controlled trials are included.
- Comparator Control
- Placebo or other analgesia drugs are used as comparators.
- Main Outcome
- The risk of post-dural puncture headahce is the primary outcome. Measures of effect Relative risk is used to estimate the effect.
- Outcome Measure
- Additional Outcome
- Severity of pain or pain relief is used as the secondary outcome. Measures of effect Relative risks or risk difference is used to measure the effect.
- Study Method
- Intervention, Meta-analysis, Systematic review
- Keyword
- Aminophylline; Anesthesia, Obstetrical; Blood Patch, Epidural; Humans; Post-Dural Puncture Headache
- Contact
- Kuo-Chuan Hung [email protected]
- Organisational Affiliation
- Chi Mei Medical center
- Funding Source
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- Taiwan
- Review Stage
- Review Ongoing
- First Submission Date
- 2020-09-04
- Registration Date
- 2020-10-05
- Anticipated Start Date
- 2020-09-04
- Anticipated Completion Date
- 2020-10-04
- Title Cn
- 氨茶碱用于预防或治疗硬脊膜穿刺后头痛：一项Meta分析
- Title En
- The use of aminophylline to prevent or treat post-dural puncture headache: a meta-analysis
- Bilingual Status
- complete