Meta AnalysisID 367
茴香对胃肠不适的影响：一项系统评价与Meta分析
CRD42015021933
Does treatment with Anise reduce symptoms of gastrointestinal discomfort?
Relationship Network
Interactive first-hop connections across herbs, ingredients, formulas, targets, diseases, symptoms, syndromes, evidence, and monographs.
Click a node to open it in a new tab
Herb: 1Meta-analysis: 1Links: 1
Arranging relationship network...
Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 367
- Evidence Id
- 8925
- Core Evidence Id
- 8925
- Source Meta Analysis Id
- 346
- Herb2 Meta Analysis Id
- HBMA000346
- Crd Id
- CRD42015021933
- Title
- The effect of anise on gastrointestinal discomfort: a systematic review and meta-analysis
- Review Question
- Does treatment with Anise reduce symptoms of gastrointestinal discomfort?
- Study Type Included
- We will include human studies, both parallel and cross-over.
- Condition Being Studied
- Gastrointestinal discomfort is a set of common symptoms, usually without known cause, which affects quality of life due to sleep disturbance and inhibition of social life (worry about embarrassment). There is no generally approved medical treatment available.
- Participant
- Inclusion criteria: Children or adults with specific symptoms of gastrointestinal discomfort, e.g. bloating, stomach cramps, stomach rumbling etc. Includes participants with Irritable Bowel Syndrome (IBS) or Postprandial Distress Syndrome (PDS) if these symptoms are assessed. Exclusion criteria: Studies focusing only on stool symptoms (e.g. stool consistency, frequency of defecation).
- Animal
- Human Disease Modelled
- Intervention
- Inclusion: Use of anise seed or other part of this plant and any product derived from anise or synthetically produced anethole, or treatments with both pure and mixed preparations.
- Comparator Control
- Anise or anise products may be compared with placebo or with control.
- Main Outcome
- 1. Intestinal Gas (Belching, Bloating, Flatulence, Rumbling). 2. Stomach upset, nausea, abdominal pain Measures of effect Timescales (from start of treatment to completion of assessment of effects) of minimum 1 day and maximum 6 months Measured using self-reported intensity of symptoms, including but not restricted to validated questionnaires. Objective measurements will also be included if they exist.
- Outcome Measure
- Additional Outcome
- 1. Constipation and diarrhoea. 2. Haemorrhoids 3. Heart burn, Gastroesophageal reflux disease (GERD), Epigastric burning 4. Early satiety, Postprandial fullness 5. Retching 6. Loss of appetite, Dysphagia 7. Cramping 8. Regurgitation 9. Any other measure defined by the investigator as a symptom of Irritable bowel syndrome [IBS] or Postprandial Distress Syndrome (PDS) Measures of effect Timescales (from start of treatment to completion of assessment of effects) of minimum 1 day and maximum 6 months Measured using self-reported intensity of symptoms, including but not restricted to validated questionnaires. Objective measurements will also be included if they exist.
- Study Method
- Keyword
- Apiaceae; Humans; Pimpinella; Seeds
- Contact
- Miss Zhang [email protected]
- Organisational Affiliation
- Newcastle University, School of Agriculture, Food & Rural Development. http://www.ncl.ac.uk/afrd
- Funding Source
- Newcastle University, represented by Dr Kirsten Brandt.
- Other Selection Criteria
- Final Publication
- Same Topic Review
- None.
- Published Protocol
- Review Type
- Language
- English
- Country
- England
- Review Stage
- Review Ongoing
- First Submission Date
- Registration Date
- 2015-08-17
- Anticipated Start Date
- 2015-06-10
- Anticipated Completion Date
- 2015-09-15
- Title Cn
- 茴香对胃肠不适的影响：一项系统评价与Meta分析
- Title En
- The effect of anise on gastrointestinal discomfort: a systematic review and meta-analysis
- Bilingual Status
- complete