Meta AnalysisID 3606
鞘内辅助哌替啶预防脊麻后寒战：随机对照试验的Meta分析与试验序贯分析
CRD42016051081
To investigate the benefits of adjuvant intrathecal meperidine with local anesthetics under spinal anesthesia.
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Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 3606
- Evidence Id
- 12164
- Core Evidence Id
- 12164
- Source Meta Analysis Id
- 3564
- Herb2 Meta Analysis Id
- HBMA003564
- Crd Id
- CRD42016051081
- Title
- Adjuvant intrathecal meperidine prevents shivering following spinal anesthesia: a meta-analysis of randomized controlled trials with trial sequential analysis
- Review Question
- To investigate the benefits of adjuvant intrathecal meperidine with local anesthetics under spinal anesthesia.
- Study Type Included
- We will include randomised trials to assess the beneficial effects of the treatment.
- Condition Being Studied
- Shivering under spinal anaesthesia.
- Participant
- Adult patients undergoing surgery under spinal anaesthesia.
- Animal
- Human Disease Modelled
- Intervention
- Shivering commonly occurs following spinal anesthesia. It causes patients discomfort and interferes with peri-operative monitoring. Present evidence for the effectiveness of shivering prevention by adjuvant intrathecal meperidine is still lacking. Trials were included if they were 1) RCTs; 2) evaluating the effects of adjuvant intrathecal meperidine in patients undergoing spinal anesthesia; and 3) contained any outcome of interest (e.g., the incidence of shivering or drug-related adverse effects). We excluded studies in which: 1) interventions were given via the oral, parenteral, or epidural routes; 2) different regimens or doses of local anesthetics were given between the experimental and the control groups; 3) meperidine was given alone without local anesthetics; 4) patients were undergoing non-elective surgery; or 5) there was duplicate reporting of patient cohorts.
- Comparator Control
- Placebo or control group. A group of patients under spinal anaesthesia without the use of intrathecal meperidine.
- Main Outcome
- The incidence and intensity of shivering after receiving spinal anesthesia before discharge from the post-anesthesia care unit.
- Outcome Measure
- Additional Outcome
- The need for rescue analgesics during the surgery and intrathecal meperidine-related complications, such as the incidence of nausea, vomiting, pruritus, hypotension, or bradycardia.
- Study Method
- Meta-analysis, Systematic review
- Keyword
- Adjuvants, Pharmaceutic; Anesthesia, Spinal; Humans; Meperidine; Postoperative Care; Postoperative Period; Shivering; Surgical Procedures, Operative; Treatment Outcome
- Contact
- Yu Cih Lin [email protected]
- Organisational Affiliation
- Funding Source
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- Taiwan
- Review Stage
- Review Ongoing
- First Submission Date
- Registration Date
- 2016-12-03
- Anticipated Start Date
- 2016-01-06
- Anticipated Completion Date
- 2017-02-10
- Title Cn
- 鞘内辅助哌替啶预防脊麻后寒战：随机对照试验的Meta分析与试验序贯分析
- Title En
- Adjuvant intrathecal meperidine prevents shivering following spinal anesthesia: a meta-analysis of randomized controlled trials with trial sequential analysis
- Bilingual Status
- complete