Meta AnalysisID 3605
半胱胺治疗胱氨酸病角膜胱氨酸结晶：系统评价和Meta分析
CRD42019146406
To evaluate the efficacy of cysteamine as a treatment for opthalamic cystinosis
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Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 3605
- Evidence Id
- 12163
- Core Evidence Id
- 12163
- Source Meta Analysis Id
- 3563
- Herb2 Meta Analysis Id
- HBMA003563
- Crd Id
- CRD42019146406
- Title
- Cysteamine for the treatment of corneal cystine crystals in cystinosis: a systematic review and meta-analysis
- Review Question
- To evaluate the efficacy of cysteamine as a treatment for opthalamic cystinosis
- Study Type Included
- We will include Randomized controlled trials
- Condition Being Studied
- Ophthalmic cystinosis (Corneal cystine crystals)
- Participant
- Inclusion: Patients with more than 1 years of age diagnosed with cystinosis and deposited corneal cystine crystals. Exclusion: Patients who were not compliant with using eye preparations and those who had other major illness besides cystinosis.
- Animal
- Human Disease Modelled
- Intervention
- Cysteamine
- Comparator Control
- Standard formulation of Cysteamine, Other cyteamine analogs, Placebo
- Main Outcome
- Change in CSSS (Corneal Cystine Crystal Score) from the baseline Measures of effect Follow up of one month or more
- Outcome Measure
- Additional Outcome
- Change in IVCM (In Vivo Confocal Microscopy) score from the baseline Cystine crystal depth Adverse events during the conduct of the studies Measures of effect Follow up one month or more
- Study Method
- Intervention, Meta-analysis, Systematic review
- Keyword
- Cornea; Corneal Opacity; Cysteamine; Cystine; Cystinosis; Humans
- Contact
- Sukhmandeep Kaur [email protected]
- Organisational Affiliation
- Niper, Mohali www.niper.nic.in
- Funding Source
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- India
- Review Stage
- Review Ongoing
- First Submission Date
- 2019-08-08
- Registration Date
- 2019-11-19
- Anticipated Start Date
- 2019-07-30
- Anticipated Completion Date
- 2019-10-31
- Title Cn
- 半胱胺治疗胱氨酸病角膜胱氨酸结晶：系统评价和Meta分析
- Title En
- Cysteamine for the treatment of corneal cystine crystals in cystinosis: a systematic review and meta-analysis
- Bilingual Status
- complete