Meta AnalysisID 3595
不同剂量甘露醇对脑水肿患者临床疗效的Meta分析
CRD42018087213
P: Patients with brain edema I: Mannitol at 20% 125ml C: Mannitol at 20% 250ml O: Intracranial pressure; nerve function, renal function, etc. S: Meta-analysis
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Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 3595
- Evidence Id
- 12153
- Core Evidence Id
- 12153
- Source Meta Analysis Id
- 3552
- Herb2 Meta Analysis Id
- HBMA003552
- Crd Id
- CRD42018087213
- Title
- The clinical efficacy of different doses of mannitol on patients with brain edema: a meta-analysis
- Review Question
- P: Patients with brain edema I: Mannitol at 20% 125ml C: Mannitol at 20% 250ml O: Intracranial pressure; nerve function, renal function, etc. S: Meta-analysis
- Study Type Included
- RCTs (randomized controlled trials).
- Condition Being Studied
- This topic has been explored with many RCTs, but no meta-analysis or systematic review has been done. Some RCTs show that a half dosage of mannitol had the same effect of decreasing intracranial pressure and changes in nerves function as the full dosage, or half dosage and double time, but had an increase in slight injury to renal function.
- Participant
- Inclusion: patients with brain edema
- Animal
- Human Disease Modelled
- Intervention
- Mannitol at 20% 125ml.
- Comparator Control
- Mannitol at 20% 250ml.
- Main Outcome
- Nerve function or ICP (intracranial pressure). Measures of effect Standard scale or Pressure.
- Outcome Measure
- Additional Outcome
- Renal function. Measures of effect BUN and Cr and AKI(acute kidney injury) incidence rate.
- Study Method
- Intervention, Meta-analysis, Systematic review
- Keyword
- Brain Edema; Brain Injuries; Humans; Mannitol
- Contact
- Shu Wang [email protected]
- Organisational Affiliation
- Sanbo Brain Hospital, Capital Medical University
- Funding Source
- None.
- Other Selection Criteria
- Final Publication
- Shu Wang, Xiaoyu Yao, Yuan Zhang, Minzhong Wang. The clinical efficacy of different doses of mannitol on patients with brain edema: A meta-analysis. Modern Medicine Journal of China. 2019 Dec, 21(12):26-31. (In Chinese with English abstract) http://new.oversea.cnki.net/kcms/detail/detail.aspx?dbcode=CJFD&filename=ZHTY201912007&dbname=CJFDTEMP
- Same Topic Review
- Published Protocol
- Review Type
- Language
- Chinese-Simplified
- Country
- China
- Review Stage
- Review Completed published
- First Submission Date
- 2018-01-26
- Registration Date
- 2018-02-05
- Anticipated Start Date
- 2018-02-05
- Anticipated Completion Date
- 2018-04-15
- Title Cn
- 不同剂量甘露醇对脑水肿患者临床疗效的Meta分析
- Title En
- The clinical efficacy of different doses of mannitol on patients with brain edema: a meta-analysis
- Bilingual Status
- complete