Meta AnalysisID 3537
镁剂治疗对蛛网膜下腔出血患者的疗效：随机对照试验的Meta分析
CRD42022346512
After subarachnoid hemorrhage, Magnesium could reduce the incidence of delayed cerebral ischemia, but its effect is still controversial. This study updated the results of recently published Magnesium-related studies and
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Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 3537
- Evidence Id
- 12095
- Core Evidence Id
- 12095
- Source Meta Analysis Id
- 3493
- Herb2 Meta Analysis Id
- HBMA003493
- Crd Id
- CRD42022346512
- Title
- Efficacy of magnesium-based therapy for subarachnoid hemorrhage patients: a meta-analysis of randomized controlled trials
- Review Question
- After subarachnoid hemorrhage, Magnesium could reduce the incidence of delayed cerebral ischemia, but its effect is still controversial. This study updated the results of recently published Magnesium-related studies and conducted an exploratory analysis of the impact of application strategies and intervention factors on the results.
- Study Type Included
- Only RCT design is eligible.
- Condition Being Studied
- Subarachnoid hemorrhage (SAH) accounts for approximately 5% of all types of stroke incidence, but this prevalence is higher among the young and middle-aged population and has an extremely poor prognosis. SAH occurs in approximately 9 per 100, 000 people every year, and half of SAH patients are younger than 55 years old and have an extremely poor prognosis. One-third of people die within three months after hemorrhage, and one-fifth of people with SAH need to rely on others to for daily activities.
- Participant
- Inclusion Criteria: Subarachnoid hemorrhage patients (Ruptured cerebral aneurysm confirmed on CT angiography or cerebral angiography) Exclusion Criteria: Age<18; Intracerebral or intraventricular haemorrhage without subarachnoid involvement.
- Animal
- Human Disease Modelled
- Intervention
- Magnesium related regimens.
- Comparator Control
- Placebo/Blank control.
- Main Outcome
- Death or persistent vegetative status;delayed cerebral ischemia;cerebral vasospasm.
- Outcome Measure
- Additional Outcome
- neurological function recovery based on modified Rankin Scale evaluation or Glasgow Outcome Scale.
- Study Method
- Intervention, Meta-analysis, Systematic review
- Keyword
- Humans; Magnesium; Magnesium Sulfate; Randomized Controlled Trials as Topic; Subarachnoid Hemorrhage
- Contact
- Xiaohong Ba [email protected]
- Organisational Affiliation
- The first affiliated hospital of jinzhou medical university
- Funding Source
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- China
- Review Stage
- Review Ongoing
- First Submission Date
- 2022-07-14
- Registration Date
- 2022-07-25
- Anticipated Start Date
- 2022-07-18
- Anticipated Completion Date
- 2022-10-01
- Title Cn
- 镁剂治疗对蛛网膜下腔出血患者的疗效：随机对照试验的Meta分析
- Title En
- Efficacy of magnesium-based therapy for subarachnoid hemorrhage patients: a meta-analysis of randomized controlled trials
- Bilingual Status
- complete