Meta AnalysisID 343
补充红曲米对代谢综合征的影响：一项系统评价与Meta分析
CRD42020209186
Is red yeast rice supplementation improve metabolic syndrome?
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Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 343
- Evidence Id
- 8901
- Core Evidence Id
- 8901
- Source Meta Analysis Id
- 323
- Herb2 Meta Analysis Id
- HBMA000323
- Crd Id
- CRD42020209186
- Title
- The effect of red yeast rice supplementation on metabolic syndrome: a systematic review andmeta-analysis
- Review Question
- Is red yeast rice supplementation improve metabolic syndrome?
- Study Type Included
- Inclusion criteria: Randomized controlled trial (RCT), controlled trial, clinical trial, randomized trial. Exclusion criteria: Case report, case series, review, animal experiments.
- Condition Being Studied
- metabolic syndrome
- Participant
- Inclusion criteria: Patients were included if they had metabolic syndrome and the components of the syndrome: elevated fasting plasma glucose, triglycerides, HDL-cholesterol, blood pressure and waist circumference, regardless of their age, sex, or nationality. The diagnostic criteria for metabolic syndrome should have met at least one of the international or domestic guidelines. Exclusion criteria: Patients were excluded if they had acute myocardial infarction, severe arrhythmia, heart failure, hepatic failure, renal failure, or acute infection.
- Animal
- Human Disease Modelled
- Intervention
- Inclusion criteria: Studies including the use of red yeast rice or xuezhikang (plus any or no other intervention) in metabolic syndrome. No limitations on blinding, dosage or treatment duration. If an add-on study design was applied, patients in the treatment group should have been treated with the same type and dosage of conventional therapy under the same standard as was used in the control group. Exclusion criteria: Studies not including the use of red yeast rice or xuezhikang in metabolic syndrome treatment.
- Comparator Control
- Inclusion criteria: All comparators (placebo, no intervention or conventional therapy) will be accepted. Exclusion criteria: Studies not including a comparator.
- Main Outcome
- triglycerides (TG), high-density lipoprotein cholesterol (HDL-C), blood pressure (BP), blood glucose, waist circumference. Measures of effect odds ratios
- Outcome Measure
- Additional Outcome
- serum total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), Body Mass Index (BMI), impaired glucose tolerance, HbA1c%, fasting insulin, insulin resistance index (HOMA-IR), cardiovascular events, adverse events. Measures of effect odds ratios, relative risks.
- Study Method
- Meta-analysis, Systematic review
- Keyword
- Biological Products; Dietary Supplements; Humans; Metabolic Syndrome; red yeast rice
- Contact
- Rong Yuan [email protected]
- Organisational Affiliation
- Xiyuan Hospital, China Academy of Chinese Medical Sciences
- Funding Source
- No
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- China
- Review Stage
- Review Ongoing
- First Submission Date
- 2020-09-14
- Registration Date
- 2020-10-15
- Anticipated Start Date
- 2020-09-07
- Anticipated Completion Date
- 2020-12-31
- Title Cn
- 补充红曲米对代谢综合征的影响：一项系统评价与Meta分析
- Title En
- The effect of red yeast rice supplementation on metabolic syndrome: a systematic review andmeta-analysis
- Bilingual Status
- complete