Meta AnalysisID 3245
环境锰暴露生物标志物与儿童神经发育的关联：一项系统评价与Meta分析
CRD42020182284
Is there a exposure-response relationship between manganese indicators or environmental samples and neurodevelopmental outcomes? Is there a correlation between manganese in environmnetal and biomarkers? which is the pote
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Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 3245
- Evidence Id
- 11803
- Core Evidence Id
- 11803
- Source Meta Analysis Id
- 3191
- Herb2 Meta Analysis Id
- HBMA003191
- Crd Id
- CRD42020182284
- Title
- Biomarkers of environmental manganese exposure and associations with childhood neurodevelopment: a systematic review and meta-analysis
- Review Question
- Is there a exposure-response relationship between manganese indicators or environmental samples and neurodevelopmental outcomes? Is there a correlation between manganese in environmnetal and biomarkers? which is the potential biomarker/source for future research?
- Study Type Included
- Original peer reviewed articles, cohort studies, cross-sectional studies, case control studies
- Condition Being Studied
- neurotoxicity, cognitive impairment, intelligence quotient (IQ), behavior problems, neuromotor
- Participant
- studies of populations up to 18 years old
- Animal
- Human Disease Modelled
- Intervention
- environmental manganese exposure ( i.e. drinking water, air or diet)
- Comparator Control
- lower levels of exposure
- Main Outcome
- neurological outcomes including IQ score, metal and psychomotor score, cognitive score, memory, behavior, hand skills, fine motor, gross motor Measures of effect IQ impairment reported as regression coefficient associated manganese in biomarker or environmental sample, expressed the change of IQ score with per specified increment in exposure
- Outcome Measure
- Additional Outcome
- none Measures of effect none
- Study Method
- Cost effectiveness, Epidemiologic, Meta-analysis, Review of reviews, Systematic review
- Keyword
- Biomarkers; Child; Child Development; Environmental Exposure; Humans; Manganese
- Contact
- weiwei liu [email protected]
- Organisational Affiliation
- zhengzhou university
- Funding Source
- the National Natural Science Foundation of China Grant number(s) <span style=font-size: 14px>State the funder, grant or award number and the date of award</span> 31530034 31930097
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- China
- Review Stage
- Review Ongoing
- First Submission Date
- 2020-05-03
- Registration Date
- 2020-07-05
- Anticipated Start Date
- 2020-05-01
- Anticipated Completion Date
- 2020-07-01
- Title Cn
- 环境锰暴露生物标志物与儿童神经发育的关联：一项系统评价与Meta分析
- Title En
- Biomarkers of environmental manganese exposure and associations with childhood neurodevelopment: a systematic review and meta-analysis
- Bilingual Status
- complete