Meta AnalysisID 3160
局部应用与静脉应用赖氨酸类似物降低输血风险的比较
CRD42016053445
How does the topical application of lysine analogues compare to the intravenous administration of lysine analogues in terms of reducing blood loos and transfusion risk?
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Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 3160
- Evidence Id
- 11718
- Core Evidence Id
- 11718
- Source Meta Analysis Id
- 3109
- Herb2 Meta Analysis Id
- HBMA003109
- Crd Id
- CRD42016053445
- Title
- Topical vs intravenous administration of lysine analogues for the reduction of transfusion risk
- Review Question
- How does the topical application of lysine analogues compare to the intravenous administration of lysine analogues in terms of reducing blood loos and transfusion risk?
- Study Type Included
- Randomized controlled trials only.
- Condition Being Studied
- Blood loss and subsequent transfusion related to either surgical or non-surgical causes.
- Participant
- Adults (18 years of age or older).
- Animal
- Human Disease Modelled
- Intervention
- Topically-administered lysine analogues.
- Comparator Control
- Intravenously-administered lysine analogues.
- Main Outcome
- Blood transfusion risk. Blood loss.
- Outcome Measure
- Additional Outcome
- Thromboembolic events. Other adverse events.
- Study Method
- Systematic review
- Keyword
- Administration, Intravenous; Administration, Topical; Blood Transfusion; Humans; Infusions, Intravenous; Lysine; Platelet Transfusion; Risk; Risk Factors; Treatment Outcome
- Contact
- Joshua Montroy [email protected]
- Organisational Affiliation
- The Ottawa Hospital Research Institute
- Funding Source
- No specific funding has been obtained for this review
- Other Selection Criteria
- Final Publication
- Same Topic Review
- CRD42016035902 Montroy J, Fergusson NA, Hutton B, Lavallée LT, Morash C, Cagiannos I, Cnossen S, Fergusson DA, Breau RH.The Safety and Efficacy of Lysine Analogues in Cancer Patients: A Systematic Review and Meta-Analysis. Transfus Med Rev. 2017 Jul;31(3):141-148. doi: 10.1016/j.tmrv.2017.03.002. Epub 2017 Mar 22.
- Published Protocol
- Review Type
- Language
- English
- Country
- Canada
- Review Stage
- Review Ongoing
- First Submission Date
- 2017-11-12
- Registration Date
- 2016-12-14
- Anticipated Start Date
- 2016-12-14
- Anticipated Completion Date
- 2017-02-03
- Title Cn
- 局部应用与静脉应用赖氨酸类似物降低输血风险的比较
- Title En
- Topical vs intravenous administration of lysine analogues for the reduction of transfusion risk
- Bilingual Status
- complete