Meta AnalysisID 3156
柠檬烯摄入量与癌症风险之间的关系：一项系统评价
CRD42020168387
What is the relationship between limonene consumption and the risk of cancer in rodents? Context and rationale In this review, we aim to find the anticancer effects of limonene on risk of different types of cancers devel
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Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 3156
- Evidence Id
- 11714
- Core Evidence Id
- 11714
- Source Meta Analysis Id
- 3105
- Herb2 Meta Analysis Id
- HBMA003105
- Crd Id
- CRD42020168387
- Title
- The relationship between limonene intake and risk of cancer: a systematic review
- Review Question
- What is the relationship between limonene consumption and the risk of cancer in rodents? Context and rationale In this review, we aim to find the anticancer effects of limonene on risk of different types of cancers development. We will review all the rodent models and make a reasonable conclusion. If we can successfully conclude that limonene has ability to treat cancer in both mice and rat models, it can be used in future studies. RCTs can also be performed based on our review to test the limonene's anticancer property.
- Study Type Included
- Inclusion criteria: No restrictions on the types of study design eligible for inclusion. Exclusion criteria: No restrictions on the types of study design eligible for exclusion.
- Condition Being Studied
- Participant
- Animal
- Inclusion criteria: Inclusion criteria: all mice and rats models with experimental cancer can develop (all species, all sexes). Exclusion criteria: Exclusion criteria: Animal models other than mice and rats; human studies; all in-vitro studies
- Human Disease Modelled
- Different types of cancer were modelled in these included studies by using rodent models.
- Intervention
- Inclusion criteria: Inclusion criteria: Any type of limonene treatment (We will not consider dosage, method, timing, and frequency. As long as the research groups used pure limonene as treatment to treat the animals, we will include these studies.) Exclusion criteria: Exclusion criteria: Not pure limonene treatment; plants or essential oils that contain limonene
- Comparator Control
- Inclusion criteria: Inclusion criteria: untreated, vehicle treated, or treated with a different intervention Exclusion criteria: Exclusion criteria: all other control conditions; use limonene as control
- Main Outcome
- Outcome Measure
- Inclusion criteria: Inclusion criteria: measure the risk of developing cancer Exclusion criteria: Exclusion criteria: do not measure the risk of developing cancer
- Additional Outcome
- Study Method
- Keyword
- Animals; Limonene; Neoplasms
- Contact
- Jingyi Zhou [email protected]
- Organisational Affiliation
- The University of Alabama https://www.ua.edu/
- Funding Source
- Dr. Lingyan Kong
- Other Selection Criteria
- Review articles and conference abstracts will be excluded.
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Pre-clinical animal intervention review
- Language
- English
- Country
- United States of America
- Review Stage
- Review Ongoing
- First Submission Date
- 2020-02-10
- Registration Date
- 2020-02-18
- Anticipated Start Date
- 2020-02-06
- Anticipated Completion Date
- 2020-08-31
- Title Cn
- 柠檬烯摄入量与癌症风险之间的关系：一项系统评价
- Title En
- The relationship between limonene intake and risk of cancer: a systematic review
- Bilingual Status
- complete